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Tuberoz Skleroz Kompleksi, İki Olgu Sunumu

Tuberous Sclerosis Complex, Two Case Reports

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Tuberous sclerosis known as Epiloia and Bourneville’s disease is a neurocutane syndrome, which is resulted from the programmed hyperplasia of ectodermal and mesodermal cells. The term tuberous sclerosis complex is now widely used. The term of the complex remarks variable multisystemic involvement and genetic heterogeneity of the disease. The disease showing different variations from the age of onset and the severity have classical triads ofepilepsy, mental retardation and adenoma sebaceum. The management of the disease is made according to the affected organ. This rarely seen disease was discussed because of the two different cases admitted to our clinics and detailed information about the cutaneous findings are given.
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Abstract (Original Language): 
Epiloia veya Bourneville hastalığı olarak da bilinen tuberoz skleroz, ektodermal ve mezodermal hücrelerin programlanmış hiperplazisinden kaynaklanan nörokutan bir sendromdur. Günümüzde tuberoz skleroz kompleksi terimi daha yaygın olarak kullanılmaktadır. Kompleks terimi, hastalığın genetik heterojenitesi yanında değişik multisistemik tutulumlarına da işaret etmektedir. Başlangıç yaşı ve şiddeti çok geniş varyasyonlar gösteren hastalığın klasik triadı; epilepsi, mental retardasyon ve adenoma sebaseum’dur. Tedavi etkilenen organa yöneliktir. Oldukça nadir görülen hastalık, kliniğimize başvuran iki farklı olgu nedeni ile tartışılmış ve uyarıcı olması gereken deri bulgularına ayrıntılı olarak yer verilmiştir.
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  • 2
123-127
  • Turkish

REFERENCES

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