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Xanthogranulomatous Epididymo-Orchitis

Ksantogranulomatöz Epididimo-Orşit

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Abstract (2. Language): 
Xantogranulomatous epididymo-orchitis is an extremely rare inflammatory disease of the testis. The process can not be distinguished clinically from a malignant testicular tumor except on histological examination. To our knowledge there are only 18 cases reported in english literature. A 34-year-old man presented with a month history of right testicular pain and swelling. Physical examination revealed severe tenderness with enlargement of the right hemiscrotum. Direct plain films and urinalysis were normal. Ultrasound examination of the right testis revealed non-homogeneous areas with poorly defined limits and hypoechoic-calcifying areas within the right testis and epididymis. A right testicular cancer was suspected and the patient had right inguinal orchiectomy. Microscopic examination showed diffuse replacement of seminiferous tubules and interstisium by sheets of foamy histiocytes intermingled with neutrophils, lymphocytes and plasma cells. Histochemical stains for organisms didn’ t yield any fungi or mycobacteria. A diagnosis of xantogranulomatous epididymo-orchitis was made.
Abstract (Original Language): 
Ksantogranülomatöz epididimo-orşit testisin, oldukça nadir görülen inflamatuar hastalığıdır. Bu durum, histopatolojik inceleme yapılmaksızın, klinik olarak malign testiküler tümörden ayırt edilemez. İngiliz literatüründe yayınlanan sadece 18 olgu mevcuttur. 34 yaşında erkek hasta, bir aydır devam eden sağ testiküler ağrı ve şişlik şikayetiyle başvurdu. Fizik muayenede sağ hemiskrotumda ciddi hassasiyet ve büyüme tesbit edildi. Radyolojik inceleme ve idrar analizleri normaldi. Ultrasonografide, sağ testis ve epididimde, sınırları belirsiz, homojen olmayan ve hipoekoik kalsifiye alanlar tesbit edildi. Sağ testis tümörü düşünülerek sağ inguinal orşiektomi uygulandı. Mikroskopik incelemede, seminifer tübüller ve interstisyumun, nötrofil, lenfosit ve plazma hücreleri ile karışık köpüksü histiositler ile yer değiştirdiği görüldü. Histokimyasal boyalarda mantar veya mikobakteri saptanmadı. Ksantogranulomatöz orşit tanısı verildi.
126-128

REFERENCES

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