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Anteriyor Mitral Kapak Prolapsusu Mitral Yetersizlik ve Panik Bozukluğa Katkıda Bulunmaktadır

Anterior Mitral Valve Prolapse Contributes to Mitral Regurgitation and Panic Disorder

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2012

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Abstract (2. Language): 
Mitral valve prolapse is affecting 2,4% of general population which shows similar prevalence, age and gender distribution and share common nonspecific symptoms with panic disorder. The aim of this prospective study is to investigate the contribution of the anterior mitral leaflet prolapse to mitral regurgitation and panic disorder. Material and Methods: Ninety-six patients, who were finally diagnosed as having noncardiac chest pain with anterior mitral valve prolapse during the evaluation of chest pain, palpitation and fatigue were assessed for panic disorder. Results: From 96 patients with mitral valve prolapse (mean age 40±8 years), 46 (48%) had panic disorder and 32 (33%) had mitral regurgitation. Majority of the patients were female (53%). 48 % of the patients with panic disorder had mitral regurgitation. Among 32 patients with mitral regurgitation, 22 (69%) had panic disorder. The incidence of panic disorder in patients with mitral regurgitation was 69%. Among those with panic disorder, 48% had mitral regurgitation. There was a significant correlation between mitral regurgitation and panic disorder (p=0.004). Conclusion: This study has demonstrated the possible contribution of the anterior mitral leaflet prolapse to mitral regurgitation and panic disorder. Panic disorder and mitral valve prolapse presents a co-morbidity, which deserves further clinical investigations.
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Abstract (Original Language): 
Amaç: Mitral kapak prolapsusu genel populasyonun %2.4’ünü etkilemektedir. Panik bozuklukla benzer sıklık, yaş ve cinsiyet dağılımı göstermekte ve ortak nonspesifik semptomları paylaşmaktadır. Bu prospektif çalışmada anteriyor mitral kapak prolapsusunun mitral yetersizlik ve panik bozukluğa katkısının araştırılması amaçlanmaktadır. Gereç ve Yöntemler: Göğüs ağrısı, çarpıntı ve halsizlik yakınması nedeniyle değerlendirlen ve sonuçta anteriyor mitral kapak prolapsusu ve non kardiyak göğüs ağrısı tanısı konulan 96 hasta panik bozukluk açısından araştırıldı. Bulgular: Mitral kapak prolapsusu olan 96 hastadan (ortalama yaş 40±8) 46’sında (%48) panik bozukluk ve 32’sinde (%33) mitral yetersizlik saptandı. Hastaların çoğunluğu (%53) kadındı ve mitral yetersizlikli 32 hastanın 22’sinde (%69) panik bozukluk vardı. Panik bozukluk saptanan hastaların %48’inde mitral yetersizlik saptandı. Mitral yetersizlikle panik bozukluk arasında istatistiksel olarak önemli korelasyon saptandı (p=0,004). Sonuç: Bu çalışmanın sonuçları anteriyor mitral kapak prolapsusunun mitral yetersizlik ve panik bozuklukla muhtemel birlikteliğini ortaya koymaktadır. Panik bozukluk ve mitral kapak prolapsusu birliktelik oluşturmakta ve bu durum daha geniş çaplı ileri çalışmalarla desteklenmelidir.
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