Buradasınız

Atopik deri hastalıklarında Staphylococcus aureus kolonizasyonu

Staphylococcus aureus Colonization in Atopic Skin Diseases

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
An epidemiologic investigation on Staphylococcus aureus (S. aureus) colonization in atopic skin diseases was conducted at İnönü University Turgut Özal Medical Center. The incidence of unaffected skin, lesional skin, and nasal positivity for S. aureus was examined in a total of 60 patients with atopic dermatitis and other atopic skin diseases. 50 healthy subjects were studied as controls. Normal skin, lesional skin, and nasal nostrils were colonized with S. aureus in 25.0%, 40.0%, and 41.7% of patients, respectively. In controls, the colonization rate of S. aureus was 2% in healthy skin and 16% in nasal nostrils (p<0.001). According to the results of antibiogram; vancomycine, tobramycine, sulbactam-ampicilline, and gentamycine were considered as the most effective drugs against S. aureus. [Journal of Turgut Özal Medical Center 1996;3(4):299-302]
Abstract (Original Language): 
Atopik deri hastalıklarında Staphylococcus aureus kolonizasyonu sıklığını belirlemek amacıyla İnönü Üniversitesi Turgut Özal Tıp Merkezinde 60 hasta ve 50 sağlıklı kişi üzerinde epidemiyolojik bir çalışma yapıldı. Hastaların; sağlam derilerinde %25.0, lezyonlu derilerinde %40.0 ve burun deliklerinde %41.7 sıklıkla S. aureus kolonizasyonu olduğu görüldü. Kontrollerin sağlıklı derilerinde %2.0, burun deliklerinde ise %16.0 oranında S. aureus üredi (p<0.001). Yapılan antibiyogramlar, S. aureus'a karşı en etkili antibiyotiklerin; vankomisin, tobramisin, sulbaktam-ampisilin ve gentamisin olduğunu gösterdi. [Turgut Özal Tıp Merkezi Dergisi 1996;3(4):299-302]

REFERENCES

References: 

1. Kemp AS, Campbell DE. New perspectives on inflammation in atopic dermatitis. J Paediatr Child Health 1996; 32: 4-6.
2. Neuber K, Konig W, Ring El-ev RA. Staphylococcus aureus and atopic eczema. Hautarzt 1993; 44: 135-42.
3. Williams RE, MacKie RM. The staphylococci. Importance of their control in the management of skin disease. Dermatol Clin 1993; 11: 201-6.
4. Goodyear HM, Watson PJ, Egan SA, et al. Skin microflora of atopic eczema in first time hospital attenders. Clin Exp Dermatol 1993; 18: 300-4.
5. Ogawa T, Katsuoka K, Kawano K, et al. Comparative study of staphylococcal flora on the skin surface of atopic dermatitis patients and healthy subjects. J Dermatol 1994;
21: 453-60.
6. Leung DY, Harbeck R, Bina P, et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 1993; 92: 1374-80.
7. Namura S, Nishijima S, Higashida T, et al. Staphylococcus aureus isolated from nostril anteriors and subungual spaces of the hand: comparative study of medical staff, patients, and normal controls. J Dermatol 1995; 22: 175-80.
8. Ventura A, Ciana G, Florean P, et al. The effect of bacterial infection in the worsening of atopic dermatitis: correlations with humoral immunologic patterns. Ann Allergy 1989; 63:
121-6.
9. Misko ML, Terracina JR, Diven DG. The frequency of erythromycin-resistant Staphylococcus aureus in impetiginized dermatoses. Pediatr Dermatol 1995; 12: 12-5.
10. Korting HC, Zienicke H, Braun-Falco O, et al. Modern topical glucocorticoids and anti-infectives for superinfected atopic eczema: do prednicarbate and didecyldimethylammoniumchloride form a rational combination? Infection 1994; 22: 390-4.

Thank you for copying data from http://www.arastirmax.com