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Enterobacteriaceae Üyesi ve Pseudomonas Cinsi Bakterilerin P-Laktam Antibiyotiklere Direnci

The resistance of Enterobacteriaceae members and Pseudomonas species to P-laktam antibiotics

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Abstract (2. Language): 
This study was performed in İnönü University Turgut ÖZAL Medical Center to asses the resistance of Enterobacteriaceae and Pseudomonas species to P-laktam antibiotics. From October 1995 to February 1997, 1126 Gram negative bacilli were isolated. 1022 (91) of isolates were Enterobacteriaceae members whereas 104 (9%) of them were Pseudomonas species. Sensitivities of pathogens P-laktam antibiotics were performed by Kirby-Bauer disc diffusion method. Following antibiotics were effective as: ceftazidime, imipenem, cefotaxime, ceftriaxone and cefoxitin for E. coli; imipenem and cefotaxime for Enterobacter species; imipenem, cefoxitin, ceftazidime, and ceftriaxone for Proteus species; imipenem, ceftazidime, cefotaxime, and ceftriaxone for Klebsiella species; imipenem and ceftazidime for Citrobacter species; and cefoperozone-sulbactam and imipenem for Pseudomonas species. [Turgut Özal Tıp Merkezi Dergisi 1997;4(2):193-196]
Abstract (Original Language): 
Bu çalışma İnönü Üniversitesi Turgut ÖZAL Tıp Merkezi Mikrobiyoloji Laboratuvarında saflaştırılan Enterobacteriaceae üyelerinin ve Pseudomonas türlerinin P-laktam antibiyotiklere in vitro direncini saptamak amacıyla yapıldı. Ekim-1995 ve Şubat-1997 tarihleri arasında klasik yöntemlerle tanımlanan 1126 Gram (-) basilden 1022'si (% 91) Enterobacteriaceae ailesi üyeleri ve 104'ü (% 9) Pseudomonas türleri idi. Patojenlerin, P-laktam antibiyotiklere karşı duyarlılık testleri Kirby-Bauer disk diffüzyon yöntemi ile yapıldı. Bulgularımıza göre E.coli için seftazidim, imipenem, sefotaksim, seftriakson ve sefoksitin'in; Enterobacter türleri için imipenem ve sefotaksim'in; Proteus'lar için imipenem, sefotaksim, seftazidim ve seftriakson 'un; Klebsiella türleri için imipenem, seftazidim, sefotaksim ve seftriakson'un; Citrobacter türleri için imipenem ve seftazidim 'in ve Pseudomonas türleri için sefaperazon-sulbaktam ve imipenem 'in en etkili olduğu tespit edilmiştir. [Journal of Turgut Özal Medical Center 1997;4(2): 193-196]
193-196

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