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İnsan göbek kordonundaki mast hücre yoğunluğu

Mast Cell Density of the Human Umbilical Cord

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1998

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Mast cells are the most constant components of the connective tissue and their presence in human placenta and umbilical cord has been described. The biological functions of mast cells in the human placenta and umbilical cord have not been well understood. The aim of the present study is to evaluate the number of mast cells of the umbilical cord in complicated and uncomplicated pregnancies. Umbilical cords obtained from 38 patients with either complicated (premature rupture of the membranes, pregnancy induced hypertension, fetal distress) or uncomplicated term pregnancies were collected immediately after spontaneous vaginal delivery or cesarean section. The mean number of mast cells from the different portion of umbilical cord were similar in all samples. There was no significant increase in the mean number of mast cells of the umbilical cord collected from uncomplicated term pregnancies delivered spontaneous vaginally compared to cesarean section. Any significant correlation was not detected in the mean number of mast cells of the umbilical cord collected from complicated pregnancies. The number of mast cells of the umbilical cord were not seemed to be affected from pregnancy complications. [Journal of Turgut Özal Medical Center 1998;5(1):43-46]
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Abstract (Original Language): 
Vücuttaki bağ dokularında bulunan mast hücrelerinin insan plasentası ve göbek kordonundaki varlığı gösterilmiş olmakla birlikte buradaki biyolojik fonksiyonları yeterince anlaşılamamıştır. Bu çalışmada komplike olan veya olmayan gebelikler deki göbek kordonlarında ortalama mast hücre sayılarının karşılaştırılması yoluyla bu konunun aydınlatılması amaçlanmıştır. Bu amaçla toplam 38 vakada göbek kordonunun fötal, orta ve maternal bölgelerindeki ortalama mast hücresi sayıları hesaplanmıştır. Yapılan istatistiksel karşılaştırmada ortalama mast hücresi sayıları göbek kordonunun değişik bölgelerinde benzer bulunmuştur. Ayrıca göbek kordonlarının içerdikleri ortalama mast hücre sayıları gebeliğin komplikasyonlu olup olmamasına ve doğum şekline göre de birbirleriyle karşılaştırılmış ve aralarında istatistiksel yönden anlamlı bir farklılığa rastlanamamıştır. [Turgut Özal Tıp Merkezi Dergisi 1998;5(l):43-46]
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  • Turkish

REFERENCES

References: 

1. Kaliner M, Lemanske R. Inflammatory responses to mast cell granules. Fed Proc 1984;43:2846-51.
2. Parwaresh MR, Horny H-P, Lennert K. Tissue mast cells in health and disease.Path Res Pract 1985;179:439-61.
3. Pagani C. I mastociti della placenta e del cordone ombelicale umani in condizioni fiziologiche. Ann Obstet Gyn
1952;74:429-42.
4. Lehner J. Das mastzellen problem und die metachromasie-Frage. Ergebn Entwickl Gesch 1924;25:67-184.
5. Engberg Damsgaard TM, Windelborg Nielsen B, Sorensen FB, Henriques U, Schiotz PO. Estimation of the total number of mast cells in the human umbilical cord. APMIS 1992;100:845-50.
6. Latta JS, Beber CR. Cells with metachromatic cytoplasmazic granules in the stroma of the human chorionic villi. Science
1953;117:498-9.
7. Pescetto G. Sulla presenza di elementi granulosi basofili metacromatici nella placenta fetale umana. Biol Lat
1957;2:744-57.
8. Longley J, Duffy TP, Kohn S. The mast cell and mast cell
disease. J Am Acad Dermatol 1995;32:4,545-61.
9. Lewis RA, Austen KF. Mediation of local homeostasis and inflammation by leukotriens and other mast cell-dependent
compounds. Nature 1981;293:103-8.
10. Gaytan F, Aceitero J, Bellido C, Sanchez-Criado JE, Aguilar E. Estrous cycle-related changes in mast cell numbers in several ovarian compartments in the rat. Biol Reprod 1991;45:27-33.
11. Silver R, Silverman A-J, Vitkovic L, Lederhendler II. Mast cells in the brain: evidence and functional significance. Trends
Neurosci 1996;19:25-31.
12. Wingren U, Enerback L. Mucosal mast cells of rat intestine: a reevaluation of fixation and staining properties, with special reference to protein blocking and solubility of the granular glycosaminoglycan. Histochem J 1983;15:571-82.
13. Sunderberg RD, Schaar FE, Powell MJS, Denboer D. Tissue mast cells in human umbilical cord. Anat Rec 1954;118:35-56.
14. Durst-Zivkovic B. Das vorkommen der mastzellen in der
nachgeburt. Anat Anz 1973;134:225-9.
15. Purcell WM, Hanahoe THP. 1.Histamine release from mast cells and basophils. A novel source of mast cells: The human
placenta. Agents Actions 1991;33-1/2:8-12.
16. Opsjon SL, Austgulen R, Waage A. Interleukin-1, interleukin-6 and tumor necrosis factor at delivery in preeclamptic
disorders. Acta Obstet Gynecol Scand 1995;74(1):19-26.
17. Hough LB. Cellular localization and possible functions for brain histamine; recent progress. Prog Neurobiol 1988;30(6):
469-505.

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