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İDRAR KÜLTÜRLERİNDE ÜREYEN NOVOBİOSİNE DUYARLI KOAGULAZ NEGATİF STAFİLOKOKLAR: KONTAMİNASYON MU, GERÇEK PATOJEN Mİ?

Novobiocine-Sensitive, Coagulase-Negative Staphylococci in Urinary Cultures: Are They Causative Agents or Contaminants?

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1999

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
A total of 66 subjects (31 asymptomatic and 35 symptomatic) whose urine culture yielded coagulase-negative staphylococci other than Staphylococcus saprophytics were evaluated both clinical and laboratory findings to figure out whether these bacteria are contaminant or causative agent. There was a good correlation between amount of colony counts and clinical symptoms. Fifteen urine samples from symptomatic people yielded > 5.1Cf CFU/ml whereas all samples from asymptomatic ones had colony counts less than 3.1(f CFU/ml. The isolates were considered as a contaminant based on less colony counts and absent of clinical symptoms showed more similar susceptibility profiles to antimicrobial agents than those with higher colony counts. In conclusion, the findings of clinical, laboratory and antibiotics susceptibility testing procedure should be considered together to make acceptable discussion about coagulase-negative staphylococci other than S. saprophytics.
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Abstract (Original Language): 
İdrar kültürlerinde üreyen S. saprophytics dışındaki koagulaz negatif stafilokokların kontaminasyon mu, gerçek patojen mi olduklarının tespit edilmesinde klinik semptomlarla laboratuar bulguları arasındaki uyum analiz edildi. Bu amaçla hastanemiz polikliniklerine başvuran 317 asemptomatik ve 357 semptomatik toplam 66 kişinin idrar örnekleri incelendi. Koloni sayısı ve klinik semptom/ar arasında anlamlı bir korelasyon tespit edildi. Semptomatik hastalardan alınan 15 örnekte > 5.1(f CFU/ml üreme olurken, asemptomatik hastalardan alınan örneklerin hiçbirinde 3.1(f CFU/m/'den daha fazla üreme olmadı. Klinik semptomları olmayan kişilerden elde edilen ve düşük sayıda koloni oluşturduğu için kontaminant olduğu düşünülen bakterilerin, antibiyotik duyarlılık profil/erindeki benzerlik yüksek sayıda koloni oluşturanlardan fazla bulundu. Bu sonuçlarla idrar kültürlerinde üreyen S. saprophytics hariç, koagulaz negatif stafilokokların kontaminasyon mu yoksa gerçek patojen mi olduklarının değerlendirilmesinde klinik semptomların, koloni sayısının ve antibiyogram sonuçlarının birlikte değerlendirilmesinin uygun olacağı söylenebilir.
FULL TEXT (PDF): 
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  • 3
225-228
  • Turkish

REFERENCES

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