The Antimicrobial Susceptibility Of Salmonella And Shigella Strains Isolated From Fecal Specimens Of Patients With Diarrhea
Journal Name:
- İnönü Üniversitesi Tıp Fakültesi Dergisi
Keywords (Original Language):
Author Name | University of Author | Faculty of Author |
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Abstract (2. Language):
In this study we aimed to determine the susceptibiiity of Salmonella (n: 30) and Shigella (n: 26) strains commonly isolated from patients having infectious diarrheae in Turgut Özal Medical Center to ampiciliin, co-trimoxazole, chloramphenicol and quinolones which are antibiotics used in empirical treatment of acute infectious diarrheae. Disk diffusion method was used to test susceptibility patterns.
All Salmonella and Shigella strains were susceptible to quinolones. The resistance percentages of Salmonella strains were 66 %, 42.3 % and 33.3 %, to ampiciliin, chloramphenicol and co-trimoxazole, respectively whlle the resistance rates of Shigella spp to the same corresponding antimicrobials were 50 %, 53.8 % and 19.2 %, respectively. From these results, it can be concluded that quinolones are the drugs of choice in empirical therapy of Salmonella and Shigella gastroenteritis. In therapy of infectious diarrhea of known etiology, results of antimicrobial susceptibility must be taken into consideration for addressing the effective antimicrobial agent.
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Abstract (Original Language):
Çalışmada Turgut Özal Tıp Merkezi Hastanesinde infeksiyöz ishallerden izole edilen 30 Salmonella ve 26 Shigella suşunun akut infeksiyöz ishallerin ampirik tedavisinde yaygın olarak kullan/lan ampisilin, kotrimoksazol, kloramfeni-kol ve kinolonlara karşı duyarhhk durumlarını beiirlemek amaçlandı. Antibiyotiklere duyarülık disk diffüzyon yöntemiyle araştırdı.
Çahşılan suşlarda kinolon grubu antibiyotiklere direnç tespit edllemedi. Ampi-siiin, kloramfenikol, kotrimoksazole Salmonella sırasıyla suşlarında; % 66, % 42.3, % 33.3, Shigella suşlarında ise; % 50, % 53.8 ve % 19.2 ve oranlarında direnç saptandı.
Bu sonuçlar, Salmonella gastroenteric ve Shigelloz'un ampirik tedavisinde ki-nolonların ilk tercih olduğunu, etkenin izole edilebildiği durumlarda ise antibiyotik duyarhhk testleri sonucuna göre antibiyotik verllmesinin gerekhiiğini göstermektedir.
FULL TEXT (PDF):
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313-316