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Menetrier Hastalığı ve Sınırlı Cerrahi Yaklaşım

MENETRIER'S DISEASE AND LIMITED SURGICAL APPROACH

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
We describe a 33 year old man who presented with fatigue, weight loss, and dark brown stool. The upper gastrointestinal X-ray series and endoscopy revealed thickened gastric folds in the cardia and corpus of the stomach. Gastic juice analysis after pentagastrin stimulation and albumin levels of serum brought to mind Menetrier's disease but histopathologic examination not. We performed celiotomy and then gastrotomy. A very fragile cerebroid pattern due to thickened and irregular folds resembling cerebroid convolutions were seen along on the cardia and corpus of the stomach. These irregular thickened mucosal folds were excised without any defect in the wall of the stomach. Histopathologic examination of the operation specimen confirmed Menetrier's disease. In the seven years since the operation the patient has had no complaint and was normal in endoscopic controls. If the giant rugae in the stomach involve a limited area then a limited resection, which is described in this study, is both effective and free from the complications of the extensive gastrectomy.
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Abstract (Original Language): 
Bu çalışmada sunulan olgu yorgunluk, kilo kaybı ve melena yakınma/arıyla başvurdu. Üst gastrointestinal radyolojik ve endoskopik incelemeler mide kardia ve korpusunda kalınlaşmış mukoza/ kıvrımları ortaya koydu. Pentagastrin uyarısı sonrası mide sıvı analizi ve serum albumin seviyeleri Menetrier hastalığını düşündürdü fakat histopatolojik inceleme Menetrier hastalığını teyit etmedi Laparatomi ve gastrotomi sonrası kardia ve korpusta frajil, kalınlaşmış, düzensiz mukoza/ kıvrımlar görüldü. Bu mukoza/ kıvrımlar mide duvarında herhangi bir defekt yaratmaksızın eksize edildi Operasyon materyalinin histopatolojik incelemesi, Menetrier hastalığını teyit etti Operasyondan yedi yıl sonra hastanın herhangi bir yakınması yoktu ve endoskopik incelemeler normaldi Menetrier hastalığında hipertrofik gastrik mukoza/ kıvrımlar sınırlı bir alandaysa, bu olgudaki gibi sınırlı mukoza/ rezeksıyon hem hastalığın ortadan kaldırılmasında etkilidir hem de gastrektominin komplikasyonlarından sakınılmış olur.
FULL TEXT (PDF): 
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  • 3
270-273
  • Turkish

REFERENCES

References: 

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