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Dizin Varus Osteoartritine Kemik Ve Kas Kitlesinin Etkisi

The Influence Of Bone And Muscle Mass On Varus Osteoarthritis Of The Knee

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2002

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
We studied 50 knees of 25 women patients with bilateral varus osteoarthritis of the knee to determine the relationship between the bone mineral density (BMD), body-mass index (BMI) and varus deformity. The mean age of patients were 66,6. Four angles were measured to assess the varus deformity of each knee: The femorotibial (FT) angle, the femoral condylar-femoral shaft (FC-FS) angle, the femoral condylar-tibial plateau (FC-TP) angle, the tibial plateau-tibial shaft (TP-TS) angle. The FC-FS/FT, FC-TP/FT and TP-TS/FT angles were also calculated to determine which component angle was predominant in the varus deformity. BMD of the L2-L4 spinal region was measured, by dual photon x-ray absorptiometry. Body-mass index (BMI), an indicator of obesity, was calculated. BMD/BMI was also calculated to determine the influence of body mass on BMD. In statistical evaluation of results a correlation was found between severity of varus osteoarthritis and low BMD and BMD/BMI (r= -0.486, p<0.05 and r=-0.403, p<0.05 respectively). There was relationship between severity of osteoarthritis and TP-TS/FT (r=0.287, p<0.05). There was a negative correlation between BMD and TP-TS/FT ( r=-0.403, p<0.05), and BMD and BMI (r=-0.551, p<0.05). In conclusion, 1 ) A low level of BMD was associated with varus deformity originating at the proximal tibia in the women with bilateral varus osteoarthritis. 2) The existence of varus knee osteoarthritis and obesity may not prevent the development of osteoporosis.
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Abstract (Original Language): 
Bilateral varus diz osteoartritine sahip 25 bayan hastanın 50 dizi, varus deformitesi ile kemik mineral yoğunluğu ve vücut-kas kitlesi arasındaki ilişkiyi belirlemek üzere değerlendirildi. Hastaların ortalama yaşı 66.6 idi. Varus deformitesini değerlendirmek için düz grafilerde; femorotibial (FT) açı, femoral kondil-femoral şaft (FK-FŞ) açısı, femoral kondil-tibia plato (FT-TP) açısı, tibial plato-tibial şaft (TP-TŞ) açısı hesaplandı. Varus deformitesi üzerinde hangi komponentin etkili olduğunu belirlemek üzere FK-FŞ/FT, FK-TP/FT ve TP-TŞ/FT oranları hesaplandı. L2-L4 vertebral bölgenin kemik mineral yoğunluğu (KMY), DEXA yöntemi ile ölçüldü. Şişmanlığın bir göstergesi olarak vücut-kas indexi (VKİ) belirlendi ve KMY/VKİ hesaplanarak KMY üzerinde vücut kas kitlesinin etkisi hesaplandı. Varus diz osteoartriti ile düşük KMY ve KMY/VKİ değerleri arasında korrelasyon mevcuttu (r= -0.486, p<0.05 ve r= -0.403, p<0.05 ). Osteoartritin şiddeti ve TP-TŞ/FT arasında bir korelasyon saptandı (r=0.287, p<0.05). KMY ve TP-TŞ/FT arasında ( r= -0.403, p<0.05) ve KMY ile VKİ arasında negatif korrelasyon mevcuttu (r= -0.551, p<0.05). Sonuç olarak, bilateral varus osteoartriti bulunan bayan hastalarda 1) düşük seviyede KMY, proksimal tibiadan kaynaklanan varus deformitesi ile birlikteydi. 2) obezite ve dizde varus osteoartritinin bulunması osteoporoz gelişmesini önleyememektedir.
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  • 2
89-93
  • Turkish

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