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Hipokalemik Tirotoksik Periyodik Paralizili Bir Olgu Sunumu

A Case With Hypokalemic Thyrotoxic Periodic Paralysis

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Abstract (2. Language): 
Thyrotoxic periodic paralysis is an uncommon complication of hyperthyroidism and characterized with the attacks of hypokalemia and muscle weakness. A male patient admitted to our emergency clinics had intermittent weakness in his upper and lower extremities which was resolving spontaneously in a few hours. Patient was diagnosed as thyrotoxic periodic paralysis depending upon laboratory examination and history. The epidemiology, pathophysiology, clinical presentation and therapy of this relatively rare disease were reviewed.
Abstract (Original Language): 
Tirotoksik periyodik paralizi hpertiroidizmin nadir bir komplikasyonudur ve hipokalemi ve kas güçsüzlüğü atakları ile karakterizedir Acil polikliniğimize başvuran bir erkek hastanın, zaman zaman tekrarlayan ve birkaç saat içinde düzelen, bacaklarında ve kollarında güçsüzlük yakınmaları mevcuttu. Anamnez ve laboratuar incelemeleri ile hastaya tirotoksik periyodik paralizi tanısı kondu. Tirotoksik periyodik paralizinin epidemiyolojisi, patofizyolojisi, klinik bulguları ve tedavisi gözden geçirildi.
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REFERENCES

References: 

1. Ko GTC, Chow CC, Yeung VTF, Chan HHL, Li JKY, Cockram CS. Thyrotoxic
periodic paralysis in a Chinese population. QJM 1996; 89: 463-8.
2. Kılpatrick RE, Seiler-Smıth S, Levine SN. Thyrotoxic hypokalemic periodic paralysis:
Report of four cases in black American males. Thyroid 1994; 4: 441-5.
3. Papadopoulos KI, Diep T, Cleland B, Lunn NW. Thyrotoxic periodic paralysis: report
of three cases and review of the literature. J Int Med 1997; 241:521-4.
4. Brown MJ, Brown DC, Murphy MB. Hypokalemia from B2 receptor stimulation by
circulating epinephrine. N Engl J Med 1983; 309:1414-9.
5. Body JJ, Cryer PE, Offord KP, Heath H. Epinephrine is a hypophosphatemic
hormone in man. J Clin invest 1983; 71: 572-8.
6. Manoukian MA, Foote JA, Crapo LM. Clinical and metabolic features of thyrotoxic
periodic parlysis in 24 episodes. Arch Intern Med.1999; 159: 601-7
7. Hochberg DA, Vassolo M, Paniagua D. Thyrotoxic period paralysis in a black man.
South Med J 1996; 89: 735-7.
8. Fontaine B, Vale-Santos J, Jurkat-Rott K, et al. Mapping of the hypokalemic periodic
paralysis (HypoPP) locus to chromosome 1q31-32 in three European families. Nat Genet 1994; 6:267-72.
9. Lin SH, Lin YF. Propranolol rapidly reverses paralysis, hypokalemia, and hypophosphatemia in thyrotoxic periodic paralysis. Am J Kidney Dis 2001; 37: 620-3.

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