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Gastrointestinal Stromal Tumour : Management in a rural Medical college in India

Gastrointestinal Stromal Tumour : Management in a rural Medical college in India

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Abstract (2. Language): 
Abstract: Gastrointestinal stromal tumour (GIST) ) is one of the most common mesenchymal tumors of the gastrointestinal tract that accounts for 1-3% of all gastrointestinal malignancies. For many years these tumors have been the subject of controversy and discussion in the literature regarding their histogenesis, diagnostic criteria, prognostic features, and nomenclature. It is now proved to originate from an intestinal pacemaker cell called the interstitial cell of Cajal. GIST may develop anywhere along the gastrointestinal tract, but most often it arises in the stomach and, less commonly in the intestine. It is a tumour that originates from spindle cells arising from muscle layer with mixed differentiation. The management depends on the histology and size of the tumour. With limited resources for advanced investigations this present case having size of 15 cms and high malignant potential was treated with resection with adequate margins.
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REFERENCES

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Photograph 1 : Tumour arising from jejunal
wall.
Photograph 2 : Tumor composed of spindle to
epithelioid cells of varying sizes & spindles
arranged in storiform pattern.
International J. of Healthcare & Biomedical Research, Volume: 1, Issue: 2, January 2013, P: 77-80
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www.ijhbr.com
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