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METHOD DEVLOPMENT AND VALIDATION OF CEFIXIME AND MOXIFLOXACIN IN PHARMACEUTICAL DOSAGE FORM BY UV SPECTROPHOTOMETRIC METHOD

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author NameUniversity of Author
Abstract (2. Language): 
Versatile, accurate, precise and economic method for determination of cefixime and moxifloxacin in fixed dose combination mixture was developed. The absorbance values at 286.0 nm and 295.0 nm and 279nm (isoabsorptive point) were used for the estimation of cefixime and moxifloxacin, respectively without mutual interference. This method obeyed Beer's law in the concentration range of 2-18 |ig /ml for cefixime and 2-12 |ig /ml for moxifloxacin. The results of analysis have been validated statistically for linearity, accuracy and precision, LOD and LOQ of the proposed method.
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  • English

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