Journal Name:
- The International Journal of Pharmaceutical Research and Bio-Science
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Abstract (2. Language):
Fast-dissolving oral delivery systems are solid dosage forms, which disintegrate or dissolve within 1 min when placed in the mouth without drinking water or chewing. More recently, fast-dissolving films are gaining interest as an alternative to fast-dissolving tablets to definitely eliminate patient's fear of chocking and overcome patent impediments. Orally fast dissolving film is the type of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within few seconds. Fast dissolving films are very similar to postage stamp in their shape, size and thickness. These films have a potential to deliver the drug systemically through intragastric, sublingual or buccal route of administration and also has been used for local action. Fast dissolving films are formulated using polymers, plasticizers, sweeteners, flavors and colors. Fast dissolving film is manufactured using solvent casting method, rolling method, extrusion method and solid dispersion method. The films evaluated for disintegration dissolution, tensile strength, thickness, folding endurance, elastic modulus
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