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ISOLATION AND CHARACTERIZATION OF CHEMICAL CONSTITUENTS OF AERIAL PARTS OF LANTANA CAMARA

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Lantana camara belongs to the family Verbenaceae, is an evergreen plant found throughout India. Traditionally it has been used in treating various ailments and they were supported by scientific data's. Various literatures have reported the phytoconstituents present in the aerial parts of Lantana camara. In our present study we have selected to isolate compound from toluene extract of the aerial parts and analyze the major constituent present in these extract by developing a novel HPLC method. The dried aerial parts were subjected for extraction with n-hexane and toluene in soxhlet apparatus. The dried toluene extract were subjected for column chromatography for the isolation of phytoconstituent. The structural analysis of the isolated compound (LC-01) was carried out by IR, NMR, MS and qualitative estimation by HPLC method using C-18 column with SPD-M20A prominence diode array detector was used. From the retention time and percentage yield (1.02%w/w) of the isolated compound obtained from toluene extract, it was concluded that compound LC-01(pentacyclic triterpenoid) were found as major chemical constituent which have structural similarities with the reference standard (Lupeol).
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FULL TEXT (PDF): 
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  • 6
198-207
  • English

REFERENCES

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ISSN: 2277-8713
IJPRBS
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Available Online At www.ijprbs.com
Research Article
Hitesh HS, IJPRBS,
2012; Volume 1(6): 198-207
ISSN: 2277-8713
IJPRBS
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