Buradasınız

Anasayfa » Content

BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM PATTERN OF LOWER RESPIRATORY TRACT INFECTIONS IN A TERTIARY CARE HOSPITAL IN NORTHERN INDIA

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Objectives. The present study was conducted to determine the bacterial aetiology and their antimicrobial susceptibility pattern of lower respiratory tract infections so as to update the clinicians in the various antimicrobial alternatives available in the treatment. Methods. 60 sputum samples from patients with lower respiratory tract infections were collected in time span of six months. Bacterial pathogens were isolated from sputum specimens, and subjected to antibiotic susceptibility testing, using standard bacteriologic techniques. Results. Out of the 60 cases, only 46 had an established bacterial aetiology. The most prevalent pathogen was Klebsiella pneumoniae followed by Staphylococcus aureus and Pseudomonas aeruginosa. Gram positive organisms showed 100% susceptibility to vancomycin, linezolid and levofloxacin. While, Gram negative isolates showed high susceptibility with aztreonam, imipenam, colistin, piperacillin/tazobactum and cefoparazone/sulbactum. Conclusions. For effective management of LRTIs bacteriological diagnosis and antibiotic susceptibility pattern is indispensable.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon ijprbs_348.pdf
  • 3
225-233
  • English

REFERENCES

References: 

1. K. Kousalya, S. Thirumurugu, D. C. Arumainayagam, R. Manavalan, J. Vasantha, and C. Uma Maheswara Reddy Antimicrobial resistance of bacterial agents of the upper respiratory tract in south Indian population. J Adv Pharm Technol Res. 2010 Apr-Jun; 1(2): 207-215. PMCID: PMC3255429
2. A. M. El- Mahmood, H. Isa1, A. Mohammed and A. B. Tirmidhi Antimicrobial susceptibility of some respiratory tract pathogens to commonly used antibiotics at the Specialist Hospital, Yola, Adamawa State, Nigeria Journal of Clinical Medicine and Research Vol. 2(8), pp. 135-142, August 2010 JCMR ISSN 2141-2235 ©2010 Academic Journals
3. B.V. Navaneeth and M.R. Sandhya Belwadi Antibiotic Resistance Among Gram-negative Bacteria of Lower Respiratory Tract Secretions in Hospitalized Patients [Indian J Chest Dis Allied Sci 2002; 44 :173-176]
4. Wenying Xia, Yi Chen, Yaning Mei, Tong Wang, Genyan Liu, Bing Gu, Shiyang Pan Changing trend of antimicrobial resistance among pathogens isolated from lower respiratory tract at a university-affiliated hospital of China, 2006-2010) 2
5. J.G. Collee, A.G. Fraser, B.P. Marmion and A. Simmons. Mackie & McCartney Practical Medical Microbiology; 14 edition, Churchill Livingstone. Chapter-4;62-66.
Available Online At www.ijprbs.com
Research
Article
Ashutosh Bhardwaj, IJPRBS, 2013; Volume 2(3):
6. Betty A Forbes, Daniel F. Sahm and Alice S. Weissfeld. Bailey & Scott's Diagnostic microbiology, 11 edition. Chapter- 18, 260- 283.
7. National Committee for Clinical Laboratory Standards (NCCLS). Performance Standards for antimicrobial susceptibility testing. 8th Informational Supplement. M100 S12. National Committee for Clinical Laboratory Standards, 2002. Villanova, Pa.
8. Nihan Ziyade, Aysegul Yagci Improving sputum culture results for diagnosis of lower respiratory tract by saline washing. Marmara Medical Journal 2010;23(1);30-36.
9. Christopher Aye Egbe, Casimir Ndiokwere, Richard Omoregie, Microbiology of Lower Respiratory Tract Infections in Benin City, Nigeria Malaysian J Med Sci. Apr-Jun 2011; 18(2): 27-31.
10. Supriya Panda, B. Prema Nandini, T.V.Ramani Lower respiratory tract infection-bacteriological profile and Antibiogram pattern. Int J Cur Res Rev, Nov 2012 / Vol 04 (21).
11. Mishra SK, Kattel HP, Acharya J, Shah NP, Shah AS, Sherchand JB, Rijal BP,
ISSN: 2277-8713
IJPRBS
Pokhrel BM Recent trend of bacterial aetiology of lower respiratory tract infections in a tertiary care centre of Nepal. Int J Infect Microbiol 2012;1(1):3-8.
12. Pokhrel BM, Koirala J, Mishra SK, et al. Multidrug resistance and extended spectrum beta lactamase producing strains causing lower respiratory tract and urinary tract infection. J Inst Med 2006;
28: 19-27.
13. Jha BK, Dey S, Tamang MD, Joshy ME, Shivananda PG, Brahmadatan KN. Characterization of candida species isolated from cases of lower respiratory tract infection. Kathmandu University Medical Journal 2006; Vol. 4, No. 3, Issue
15, 290-294
14. A.O. Okesola and O.M. Ige Trends in Bacterial Pathogens of Lower Respiratory Tract Infections. Indian J Chest Dis Allied
Sci 2008; 50: 269-272.
15. H.B. Veena Kumari, S. Nagarathna and A. Chandramuki Antimicrobial Resistance Pattern Among Aerobic Gramnegative Bacilli of Lower Respiratory Tract Specimens of Intensive Care Unit Patients in a Neurocentre. Indian J Chest Dis Allied
Sci 2007; 49: 19-22.

Thank you for copying data from http://www.arastirmax.com