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GASTROÖZOFAGEAL REFLÜNÜN ASTIM ETYOPATOGENEZİNDEKİ YERİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 1998

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Abstract (2. Language): 
The value and imporlance of gastroesophageal reflux in asthma etiopathogenesis. Gastroesophageal reflux is an important factor at the beginning of asthma disease. Our ptırpose is to understand these relations and to observe the imporlance of gastroesophageal reflux in asthma patients wlıich have been seen frequently in our clinic. 15 children between 2-14 years old which have asthma disease were included in research groııp at Haydarpaşa Numune Hostipal, Pediatric Clinic during on March 1994-February 1995. At the other hand, 15 children between 2¬12 years old which haven't asthma or gastroesophageal reflux symptoms were included in control groııp. Ali children vvere observed vvitlı 24 hours esophageal Plı monitoring and we used the percentage of time Ph, the number of reflux episodes, the number of episodes lasting more than 5 minutes the duration of the longest episodes, the percentage of upright and supine refluxes time, Ihe number of reflux in an hour, the longest reflux time in an hour, the mean time of reflux in an hour as parameters in both groups. As a statistical review, we found pasitive differences in only twq research group parameters and one of them was the percentage of time PH and the other was the number of reflux episodes. As a conclusion, it is assumed that gastroesophageal reflux is very important factor in asthma etipathogenesis and the best methods evaluating gastroesophageal reflux is 24 hours Ph monitoring.
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Abstract (Original Language): 
Klinikte sık olarak rastladığımız astımlı hastalarda gastroözofageal reflünün (GÖR) önemini ortaya koymak amacıyla Haydarpaşa Numune Hastanesi, Çocuk Kliniğinde Mart 1994 Şubat 1995 yılları arasında yatarak tedavi gören, yaşları 2-14 yıl arasında değişen, 15 astım semptomlu çocuktan çalışma grubu oluşturuldu. Astım ve GÖR'e yolaçacak patolojisi olmayan 2-12 yaşları arası 15 çocuk da kontrol grubu olarak seçildi. Tüm çocuklara, 24 saatlik özofageal Ph-monitorizasyonu yapılarak toplam reflü zamanının yüzdesi, toplam reflü sayısı, 5 dakikadan uzun reflü sayısı, en uzun reflü süresi, ayakta ve yatarken reflü zamanının yüzdesi , saatteki reflü sayısı, dakikada ortalama reflü süresi incelendi. Toplam reflü zamanının yüzdesi ve toplam reflü sayısında istatiksel olarak çalışma grubu lehine anlamlıya yakın farklılık belirlendi (p>0.05). Sonuçta astım etyopato genezinde GÖR'ün de önemli bir yer tuttuğu ve ayırıcı tanıda mutlaka araştırılması gerektiği kanısına varıldı.
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  • 4
415-418
  • Turkish

REFERENCES

References: 

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