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MENOPOZ ÖNCESİ VE SONRASI ŞİŞMAN KADINLARDA YAĞ MİKTARI VE YAĞ DAĞILIMI İLE RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ

SUMMARY Body weight, body fat distribution and metabolic risk factors in pre-and postmenopausal obese women

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 1999

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The aim of this study in to examine body weight, body fat distribution and metabolic risk factors in postmenopausal obese women and to compare the postmenopousal wo-men's finding with premenopousal obese vvomen. Study group is consisted of 1475 obese (body mass index, BMI > 27 kg/m2) women. 355 patİent were in the postmenopausal status (24 %). Total (232.34+43.26 and 201.21±39.17 mg/dl) and LDL-cholesterol (149.69±41.28 and 126.36i35.25 mg/dl), triglyccridcs (179.90+95.00 and 152.53±87.07 mg/dl), systolic (152.57+31.10 and 136.66±25.83 mmHg) and diastolic biood pressure (94.34il6.44 and 88.55+14.22 mmHg), glucose (109.74i35.21 and 98.57il8.42 mg/dl), uric acid (4.93+1.44 and 4.43İİ.18 mg/dl), weight (91.41+16.72 and 88.83+16.99 kg), BMI (38.17+7.11 and 35.91i6.83 kg/m2), waist-to-hip ratio (0.83+0.08 and 0.79+0.07) intraabdominal fat (IAF, 149.12+39.96 and 118.10+38.89 cm2; 3.97İ2.17 and 3.19Ü.42 kg) and waist circumfcrencc (103.12il3.78 and 96.26il3.13 cm) levels were sİgnificantly higher in postmenopausal group than premenopausals (p for wcght 0.012, for others<0.001). These findings suggest that inere-ased abdominal fat tİssue may have adverse effects on metabolic risk factors in postmenopausal women. In addition total fat which is determined by wcight and BMI may also contribute to elevated levels of metabolic risk factors.
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Abstract (Original Language): 
Bu çalışma şişman postmenopozal kadınlarda vücut ağırlığnıı,yağ dağılımını ve obeziteye eşlik eden metabolİk risk göstergelerini incelemek ve bulguları menopoz öncesi şişman kadınlarla karşılaştırmak amacıyla gerçekleştirildi. Çalışma kapsamına alman 1475 şişman (vücut kitle indeksi, BMI > 27 kg/m2) kadından 355 i menopoz sonrasi dönemde İdi (% 24). Menopoz sonrası kadınlarda menses görenlere göre total (232.34±43.26 ve 20.21+39.71 mg/dl) ve LDL-ko-lesterol (149.69+41.28 ve 126.36±35.25 mg/dl), trigliserid (179.90±95.00 ve 152.53±87.07 mg/dl),sistolik (152.57±31.10 ve 136.66+25.83 mm Hg) ve diastolik damar basıncı (94.34±16.44 ve 88.55+14.22 mmHg), glukoz (İ09.74+35.21 ve 98.57+18.42 mg/dl), ürik asit (4.93+1.44 ve 4.43İİ.18 mg/dl), ağırlık (91.41±16.72 ve 88.83il6.99 kg), BMI (38.17±7.11 ve 35.91+6.83 kg/m2), bel-kalça oram (0.83+0.08 ve 0.79+0.07), intraabdominal yağ miktarı (TAF, 149.12+39.96 ve 118.10+38.89 cm2; 3.97+2.17 ve 3.19+1.42 kg) ve bel çevresi (103.12+13.78 ve 96.26+13.13 cm) anlamlı yüksek bulundu (p; ağırlık için 0.012, diğerleri için <0.001). Plazma lipid düzeyleri menopoz sonrası kadınlarda menses görenlere göre daha yüksek bulunmaktadır. Menopoz sonrası kadınlarda ağırlık ve BMI ne ek olarak intraabdominal yağ miktarı, bel çevresi ve bel/kalça oranlarının da anlamlı yüksek bulunması menopozu takiben artan batın İçi yağ miktarınrn risk faktörlerinin düzeyini yükseltebileceğini düşündürmektedir. Bununla birlikte ağırlık ve BMI ile değerlendirilen total yağ miktarının da risk faktörlerine katkısı olabileceği hatırlanmaktadır.
FULL TEXT (PDF): 
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  • 3
295-300
  • Turkish

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