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SIÇANLARDA ABDOMİNAL ADA FLEBİ MODELİNDE VENÖZ OKLÜZYON SÜRESİ İLE REPERFÜZYON HASARININ İLİŞKİSİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The relation between venous ocelusion peri od and reperfusion injury in abdominal flep of rats. Skin flep failure is a commonly eııcountered problem in venous insufficiency. A standart model of reperfusion injury due (o venous stasıs in the epigastrik artery and vein based abdominal flep of rats was created in order to evaluate treatment choices of venous stasıs. Fi-ve groups each consisting of eight animals were performed. A 5x3 cm3 neurovascular skin is-land fiap based on the inferior epigastrik artery and vein was raised and vein was clamped. Af-ter two hours in fırst group, five hours in second group, seven hours in third group, nine hours in fourth group and ten hours in fifth group elamps were removed and mean survival rate of flaps were %100, 100%, 82%, 20%, and 3% respeetively. As wide sprcad reperfusion injury and "reflow" was possible
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Abstract (Original Language): 
Veııöz yetmezlik sonucu aksiyal devi fleplerinde doku kaybı sık karşılaşılan bir problemdir. Çalışmamızda, venöz staz sonrası tedavi seçeneklerini değerlendirebilmek amacıyla,sıçanlarda epİgasrik arter ve ven pcdiküllü nörovasküler abdominal ada flebinde standart bir venöz staz hasan modeli oluşturulmuştur. 5 ayrı grup sıçannın (n=8) 5x3 cm3 abdominal ada flebinde epi-gastrik ven 2, 5, 7, 9 ve 10 saat süreyle klemplenerek venöz staz sağlanmıştır. Bu süreler sonunda reperfüze edilen fleplerde sırasıyla %100, %100, %82, %20 vc %3'luk ortalama canlı flep alanlarına ulaşılmıştır. Hem yaygın doku hasarı oluşması, hemde 'reflow' gözlenmesi nedeniyle dokuz saatlik venöz staz süresi ideal venöz staz süresi olarak değerlendirilmiştir
FULL TEXT (PDF): 
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  • 4
371-374
  • Turkish

REFERENCES

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