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VAN VE ÇEVRESİNDE SAPTANAN MİDE KANSERLERİNİN LOKALİZASYONU VE HİSTOPATOLOJİK ÖZELLİKLERİ: 466 OLGUNUN ANALİZİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The hislopathologicai caharacterisiics and localization ofgastric cancer in Van and Us aro-und. The past thirty years it is known that the distal localization of adenocarcinomas was in a trend of decrease and proximal adenocarcinomas inereased. It has been claimed that the decre-ase in the incidence of distal adenocarcinomas was assocİated with the decrease in the inciden-ce of Helicobacter pylori. In this study 459 cases who wcre diagnosed to have gastric cancer within the years of 1995-2001 in the gastroenterology department of the Research Hospital of Yuzuncu Yil University were retrospecüvely evaluated. As for the localizatİons, our cases re-vealed the followİng manİfestatİons: 163 cases middlc stomach; 159 distal stomach; and 132 proximal stomach; 5 cases were deteeted to have diffused involvement. Mean age of ali cases was found to be 56.7 (aged between 17-91). Maie/female range was found as 1.9 and seventy-four percent of our cases were aged between 40-70. The youngest age for the condition to be prevailed was 25 in the males and 17 in females. The hislopathologicai characteristİcs of our cases were conceived as thus: 451 cases adenocarcinoma; 7 cases squamous celi carcİnoma and a single one was deteeted to have small celi carcİnoma. In conclusİon: İn spite of the facî that in the recent years therc İs a remarkabİc inerease in the prevalence of projcimal gastric cancers, the middle localizatİons of the stomach were found to be the most commonly-obser-ved involvement in our series. Forty-three percent of them were found Helicobacter pylori po-sitive in tİssue (53% antrum, 45% corpus and 28% cardia).
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Abstract (Original Language): 
Geçen 30 yıl içinde, gelişmiş ülkelerde midenin dİstal yerleşimli adenokanserlerİnin azaldığı, proksİmal adenokanserlerİnin arttığı bildirilmektedir. Distal adenokanserlerin sıklığındaki azalmanın, Helicobacter pylori eradikasyonu ile paralellik gösterdiği iddia edilmektedir. Bu çalışmada 1995-2001 yılları arasında Yüzüncü Yıl Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim Dalı'nda endoskopik ve histolojik olarak mide kanseri tanısı almış 459 olgu retrospektif olarak değerlendirildi. Olguların 304'ü (%66) erkek, 155'i (%34) kadın idi. Yaş ortalaması 56.7±12.4 (17-91 yaş arası) olup, erkek/ kadın oranı 1.9 olarak tespit edildi. Olguların %74'ü 40-70 yaş arasında olup, en küçük görülme yaşı erkeklerde 25, kadınlarda 17 olarak bulundu. Lokalizasyon olarak; olguların 163'ü (%35.5) mide orta kısım, 159'ü (%34.6) 1/3 mide distal, 132'si (%28.7) 1/3 mide proksimal, 5'i (%1) diffüz tutulum gösteriyordu. Histopatoiojik özellikleri; 451'i (%98) adenokanser, 7'si (%1.5) epidermoid, biri küçük hücreli kanser idi. Sonuç olarak; son yıllarda proksimal gastrik kanserlerin sıklığında belirgin artış gözlenmesine rağmen, serimizde korpus lokalizasyonu en yaygın tutulum yeri olarak belirlendi. Olguların ortalama %43'ünde doku düzeyinde (antrum %53, koıpus %45, kardia %28) Helicobacter pylori pozitif bulundu.
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  • 1
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  • Turkish

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