A CASE OF NEUROBRUCELLOSIS PRESENTING WITH PAPILLITIS
Journal Name:
- İstanbul Tıp Fakültesi Dergisi
Key Words:
Keywords (Original Language):
Abstract (2. Language):
Neurologic complications of childhood brucellosis are rarely seen. It usually presents as acute infection of central
nervous system. A9-year-old female patient presented to our clinic with fatigue, severe headache, visual loss especially
at right eye. She had a history of cheese ingestion made from unpasteurized milk four months ago. There was
bilateral papilledema and hemorrhagia at optic discs in fundoscopic examination. Standart Brucella tube agglutination
(Wright test) was positive at 1/320 titer and Coombs test was strongly positive at 1/1280 titer. Brucella IgG was
also positive (ELISA) in cerebrospinal fluid examination. She was treated with doxycylin, rifampicin and gentamicin.
Her clinical findings improved after treatment. No relapse was seen in 10-month follow-up period.
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Abstract (Original Language):
Brusellozisin çocukluk ça¤›nda nörolojik komplikasyonlar› nadir görülür ve genellikle santral sinir sisteminin akut
enfeksiyonu fleklinde seyreder. Dokuz yafl›nda k›z hasta, klini¤imize halsizlik, fliddetli bafl a¤r›s›, sa¤ gözde daha
belirgin olmak üzere bilateral görmede azalma flikayeti ile baflvurdu. Dört ay önce pastörize edilmemifl sütten yap›
lm›fl peynir yeme hikayesi bulunan hastada, optik diskin fundoskopik muayenesinde bilateral papilla ödemi ve
hemoraji vard›. Serumda standart brusella tüp aglütinasyon testi (Wright testi) 1/320 titrede (+), Coombs ile 1/1280
titrede (+), beyin omurilik s›v›s›n›n EL‹SA ile incelenmesinde brusella IgG (+) olarak saptand›. Doksisiklin, rifampisin
ve gentamisin ile tedavi edildi. Tedaviden dört hafta sonra papilla ödemi geriledi ve 8 hafta sonunda tamamen
iyileflti. On ayl›k izlemde relaps gözlenmedi.
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