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İMPLANTLARIN ERKEN DÖNEM BAŞARISINA PROFLAKTİK ANTİBİYOTİK KULLANILMASININ ETKİSİ

The Influence of Prophylactic Antibiotics on Early Time Success of Dental Implants

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Abstract (2. Language): 
Purpose: The purpose of this retrospective study was to compare the efficacy of the pre-operative prophylaxis plus 5-days post-operative dosing and only 5-days post-operative dosing with no-antibiotics use. Material and Methods: 150 dental implant patients and 403 implants were included to the study. Complications (infection, implant loss, wound dehiscence and hemorrhage) and patient’s complaints (pain, edema, hematoma, gastrointestinal complaints) were evaluated. Results: No patients were reported any gastrointestinal complaints and hemorrhage. The majority of the patients had edema after implant surgery. No significant differences with regard to rest of the complications and patients complaints were found in the study. Conclusion: According to the results of this study, prophylactic antibiotic use for 5-days in implant surgery does not have benefit over any antibiotics use. Long-term randomized studies with higher numbers of patients are needed to provide more credible evidence.
Abstract (Original Language): 
Amaç: Bu retrospektif çalışmanın amacı pre-operatif doz ile birlikte post-operatif 5 gün veya sadece post-operatif 5 gün boyunca antibiyotik profilaksisi yapılması ile hiç antibiyotik kullanılmamasının etkinliğini karşılaştırmaktır. Gereç ve Yöntem: Çalışmaya 150 hasta 403 implant dâhil edilmiştir. Komplikasyonlar (enfeksiyon, implant kaybı, yara kenarında açılma, kanama) ve subjektif hasta şikayetleri (ağrı, ödem, hematom, gastrointestinal şikâyet) değerlendirilmiştir. Bulgular: Hiçbir hasta gastrointestinal şikâyet veya hemoraji bildirmemiştir. Hastaların çoğunda ödem görülmüştür. Çalışma grupları arasında diğer komplikasyonlar ve şikâyetler arası istatistiksel olarak anlamlı fark bulunmamıştır. Sonuç: Bu çalışmanın sonuçları, 5 gün süre ile uygulanan antibiyotik profilaksisinin hiç antibiyotik kullanılmamasına göre üstünlük kazandırmadığını göstermektedir. Kesin sonuçlara varmak için hasta sayısının yüksek olduğu uzun dönemli randomize takip çalışmaları gerekmektedir.
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REFERENCES

References: 

1. Maestre Vera JR, Gómez-Lus Centelles
ML. Antimicrobial prophylaxis in oral surgery
and dental procedures. Med Oral Patol
Oral Cir Bucal, 2007; 12(1): E44-52.
2. Peterson LJ. Antibiotic prophylaxis
against wound infections in oral and maxillofacial
surgery. J Oral Maxillofac Surg,
1990; 48(6): 617-20.
3. Olson M, O’Connor M, Schwartz ML.
Surgical wound infection: a 5-year prospective
study of 10193 wounds at the Minneapolis
VA Medical Center. Ann Surg, 1984;
199(3): 253-59.
4. Boyle N, Gallagher C, Sleeman D. Antibiotic
prophylaxis for bacterial endocarditis--
a study of knowledge and application of
guidelines among dentists and cardiologists.
J Ir Dent Assoc, 2006; 51(5): 232-37.
5. Gould FK, Elliott TS, Foweraker J,
Fulford M, Perry JD, Roberts GJ, Sandoe
JA, Watkin RW. Guidelines for the prevention
of endocarditis: report of the Working
Party of the British Society for Antimicrobial
Chemotherapy. J Antimicrob Chemother,
2006; 57(6): 1035-42.
6. Wilson W, Taubert KA, Gewitz M,
Lockhart PB, Baddour LM, Levison M, Bolger
A, Cabell CH, Takahashi M, Baltimore
RS, Newburger JW, Strom BL, Tani LY, Gerber
M, Bonow RO, Pallasch T, Shulman ST,
Rowley AH, Burns JC, Ferrieri P, Gardner
T, Goff D, Durack DT; American Heart Association.
Prevention of infective endocarditis.
Guidelines from the American Heart
Association: a guideline from the American
Heart Association Rheumatic Fever, Endocarditis
and Kawasaki Disease Committee,
Council on Clinical Cardiology, Council on
Cardiovascular Surgery and Anesthesia, and
the Quality of Qare Outcomes Research Interdisciplinary
Working Group. J Am Dent
Assoc. 2008; 139 suppl: 3S-24S. Erratum in:
J Am Dent Assoc, 2008; 139(3): 253.
7. Page CP, Bohnen JMA. Antimicrobial
prophylaxis for surgical wounds: Guidelines
for clinical care. Arch Surg, 1993; 128(1):
79-88.
8. Dent CD, Olson JW, Farish SE, Bellome
F, Casino AJ, Morris HF, Ochi S. The
influence of preoperative antibiotics on
success of endosseous implants up to and
including stage II surgery: a study of 2,641
implants. J Oral Maxillofac Surg, 1997;
55(12 Suppl 5): 19-24.
9. Göran W, Gynther, Per Ake Kandell,
N. Bölükbaşı, S. Yeniyol, T. Özdemir
45
Moberg LE, Heimdahl A. Dental implant
installation without antibiotic prophylaxis.
Oral Surg Oral Med Oral Pathol Oral Radiol
Endod, 1998; 85(5): 509-11.
10. Larsen P, McGlumphy E. Antibiotic
prophylaxis for placement of dental implants.
J Oral Maxillofac Surg, 1993; 51: 194.
11. Laskin D, Dent C, Morris H. The Influence
of preoperative antibiotics on success
of endosseous implants at 36 months. Ann
Periodontol, 2000; 5(1): 166-74.
12. Mazzocchi A, Passi L, Moretti R. Retrospective
analysis of 736 implants inserted
without antibiotic therapy. J Oral Maxillofac
Surg, 2007; 65(11): 2321-23.
13. Peterson LJ. Long term antibiotic
prophylaxis is not necessary for placement
of dental implants. J Oral Maxillofac Surg,
1996; 54 (Suppl3): 76.
14. Esposito M, Cannizzaro G, Bozzoli
P, Checchi L, Ferri V, Landriani S, Leone
M,Todisco M, Torchio C, Testori T, Galli
F, Felice P. Effectiveness of prophylactic
antibiotics at placement of dental implants:
a pragmatic multicentre placebo-controlled
randomised clinical trial. Eur J Oral Implantol,
2010; 3(2): 135-43.
15. Binahmed A, Stoykewych A, Peterson
L. Single preoperative dose versus long-term
prophylactic antibiotic regimens in dental
implant surgery. Int J Oral Maxillofac Implants,
2005; 20(1): 115-17.
16. Karaky AE, Sawair FA, Al-Karadsheh
OA, Eimar HA, Algarugly SA, Baqain
ZH. Antibiotic prophylaxis and early dental
implant failure: a quasi-random controlled
clinical trial. Eur J Oral Implantol, 2011;
4(1): 31-38.
17. Gynther GW, Köndell PA, Moberg
LE, Heimdahl A. Dental implant installation
without antibiotic prophylaxis. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod,
1998; 85(5): 509-11.
18. Mombelli A. Microbiology of the
dental implant. Adv Dent Res, 1993; 7(2):
202-06.
19. Bölükbaşı N, Özdemir T, Öksüz L,
Gürler N. Bacteremia following dental implant
surgery: preliminary results. Med Oral
Patol Oral Cir Bucal, 2012; 17(1): e69-75.
20. Maestre JR, Giménez MJ, Bascones
A et al. Odontopathogen susceptibility to
amoxicillin/clavulanic acid and other common
antibiotics used in odontology. 7th
European Congress of Chemotherapy and
Infection. October 19-22, Florence, Italy.
2005, p.209.
21. Brescó-Salinas M, Costa-Riu N,
Berini-Aytés L, Gay-Escoda C. Antibiotic
susceptibility of the bacteria causing odontogenic
infections. Med Oral Patol Oral Cir
Buccal, 2006; 11(1): E70-75.
22. Paterson JA, Cardo VA, Stratigos GT.
An examination of antibiotic prophylaxis in
oral and maxillofacial surgery. J Oral Surg,
1970; 28: 753-59.
23. Lang NP, Wet, AC. Histologic probe
penetration in healthy and inflamed periimplant
tissues. In: Brånemark, P.-I., Zarb,
G.A. & Albrektsson, T. eds. Tissue-Integrated
prostheses: osseointegrationin clinical
dentistry. Chicago: Quintessence, 1985;
p.211-32.
24. Quirynen M, De Soete M, van Steenberghe
D. Infectious risks for oral implants: a
review of the literature. Clin Oral Impl Res,
2002; 13(1): 1-19.
25. Arısan V, Bölükbaşı N, Oksüz L.
Computer-assisted flapless implant placement
reduces the incidence of surgery-related
bacteremia. Clin Oral Investig, 2012 Dec 6.
26. Piñeiro A, Tomás I, Blanco J, Alvarez
M, Seoane J, Diz P. Bacteraemia following
dental implants’ placement. Clin Oral Imİmplantların
Erken Dönem Başarısına Proflaktik Antibiyotik Kullanılmasının Etkisi
46
plants Res, 2010; 21(9): 913-18.
27. van Winkelhoff AJ. Antibiotics in the
treatment of peri-implantitis. Eur J Oral Implantol,
2012; 5 Suppl: S43-50.
28. Alanis A, Weinstein AJ. Adverse reactions
associated with the use of oral penicillins
and cephalosporins. Med Clin North Am,
1983; 67(1): 113-29.

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