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DİŞ ETİ BÜYÜMESİ MEYDANA GETİREN İLAÇLAR VE TEDAVİLERİ

Drug Induced Gingival Overgrowth and Its Management

Journal Name:

  • İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 2013

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Gingival overgrowth (GO) that associated with phenytoin tharapy was first reported in the dental literature in 1939 by Kimball. Recently, cyclosporine and numerous calcium channel blocker agents have been associated with GO. The etiology of drug-induced GO is not entirely understood but is clearly multifactorial. Some of the risk factors known to contribute to GO include the presence of gingival inflammation, presence of dental plaque, the depth of the periodontal pocket on probing, and the dose and duration of cyclosporine therapy. An oral medicine specialist and a periodontist should monitor patients with GO for as long as they receive therapy with cyclosporine, phenytoin, or calcium channel blockers to evaluate and treat oral complications from medical therapy
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Abstract (Original Language): 
Fenitoin tedavisine bağlı olarak oluşan diş eti büyümesi ilk olarak 1939 yılında Kimball tarafından rapor edilmiştir. Günümüzde, siklosporin ve kalsiyum kanal blokerlerinin diş eti büyümesi ile ilişkili olduğu bilinmektedir. İlaca bağlı diş eti büyümelerinin nedeni tam olarak açığa kavuşturulamasa da, multi-faktöriyel olduğu açıktır. Diş eti enflamasyonu, dental plak varlığı, periodontal cep derinliği, siklosporin tedavisinin dozu ve süresi gibi bazı etkenlerin risk faktörü olduğu ve diş eti büyümesini tetiklediği düşünülmektedir. Diş eti büyümesi olan hastalar, siklosporin, fenitoin veya kalsiyum kanal blokeri tedavisi aldığı sürece, medikal tedaviye bağlı gelişen komplikasyonların değerlendirilmesi ve tedavisi için bir ağız hastalıkları ve periodontoloji uzmanı tarafından izlenmelidirler.
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