MODELING ELF ELECTROMAGNETIC FIELD EFFECTS ON SKIN’S HYDROXYPROLINE LEVEL USING NEURAL NETWORKS

[1] Tenford, T.S., “Interaction of ELF
Magnetic Fields with Living Matter” in CRC
Handbook of Biological Effects of
Electromagnetic Fields (POLK, C.,
POSTOW, E., eds.), CRC Press, Boston,
197-228, 1986
[2] Frey, A., On the Nature of
Electromagnetic Field Interactions with
Biological Systems, Austin, USA: Landes
Company, Medical Intelligence Unit, R.G.
,1994
[3] Tenforde, T.S., “Biological Responses to
Static and Time-Varying Magnetic Fields” in
Electromagnetic Interaction with Biological
Systems (LIN, J.C., ed.), 83-108, Plenum
Press, New York, 1989
[4] Polk, C., Introduction in CRC Handbook
of Biological Effects of Electromagnetic
Fields (Polk, C., Postow, E., eds.), 1-27, CRC
Press, Boston, 1986
[5] Kanje, M., Rusovan, A., Sısken, B.,
Lundborg, G., “Pretreatment of Rats with
Pulsed Electromagnetic Fields Enhances
Regeneration of the Sciatic Nevre”,
Bioelectromagnetics, 14, 353-359, 1993
[6] Frank, C., Schachar, N., Dıttrıch, D.,
Shrıve, N., Phıll, D., Dehaas, W., Edwards,
G., “Electromagnetic Stimulation of
Ligament Heling in Rabbits”, Clin. Orth. Rel.
Res., 175, 263-271, 1983
[7] Leaper, D.J., Foster, M.E., Brennan, S.S.,
Davıes, P.W., “Experimental Study of the
Influence of Magnetic Fields on Tissue
Wound Healing”, J. Trauma, 25, 1083-1084,
1985
[8] Hınsenkamp, M., Tuerlınckx, B., Rooze,
M., “Effects of ELF Fields on Bone Growth
and Fracture Repair” in Biological Effects
and Dosimetry of Static and ELF
Electromagnetic Fields (GRANDOLFO. M.,
MICHAELSON, S.M., RINDI, A., eds.),
441-446, Plenum Press, New York, 1985
[9] Garcıa, P.G., De La Cal, A.M.,
“Enhancement of Bone Healing by an
Exogenous Magnetic Field and the Magnetic
Vaccine”, J. Biomed. Eng., 7, 157-160, 1985
[10] Gupta, T.D., Jaın, V.K., Tandon, P.N.,
“Comperative Study of Bone Growth by
Pulsed Electromagnetic Fields”, Med. Biol.
Eng. Comput., March, 113-120, 1991
Modeling Elf Electromagnetic Field Effects On Skin’s Hydroxyproline Level
Using Neural Networks
Ayşe G. CANSEVEN, Gülay TOHUMOGLU, Abdükadir ÇEVİK, Nesrin SEYHAN
448
[11] Canseven AG., “Electrical Properties of
the Skin.” Gazi Med J 3: 41- 46, 1992.
[12] Canseven AG, Atalay Seyhan N., “Is It
Possible to Trigger the Collagen Synthesis by
Electric Current in Skin Wounds?” Indian J
Biochem Biophys 33: 223-227, 1996.
[13] Canseven AG, Atalay Seyhan N., “Electric
Current-Collagen Synthesis Interaction in
Wound Healing –I.” Turkish Med J, Turkish ,
2 : 71-77, 1995.
[14] Canseven A.G., Seyhan N., “Do 50 Hz
Magnetic Fields Affect Skin’s Collagen
Synthesis?”, Indian Journal of Biochemistry
and Biophysics, Nov. 2006 (accepted).
[15] Güler G, Atalay Seyhan N., “Changes in
Hydroxyproline Levels in Electric Field
Tissue Interaction.” Indian Journal
of Biochemistry and Biophysics 33 : 531-533,
1996.
[16] Canseven A.G., Seyhan N., “Çevresel
ELF Manyetik Alanların Etkileri : Kobay
Deri Kollagen Sentezinde Değişimler ve
Deney Hayvanından İnsana Ölçülendirme,”
Gazi Tıp Dergisi, 16 (4) : 160 – 165, 2005
[17] Mevıssen, M., Wahnschaffe, U., Löscher,
W., Stamm, A., Lerchl, A., “Effects of AC
Magnetic Fields on DMBA-Induced
Mammary Carcinogenesis in Sprague-
Dawley Rats” in Electricity and Magnetism
in Biology and Medicine (BLANK, M., ed),
413-415, San Francisco Press, Inc., USA
(1993)
[18] de Seze, R., Bouthet, C., et al., “Effects of
Time-Varying Uniform Magnetic Fields on
Natural Killer Cell Activity and Antibody
Response in Mice.” Bioelectromagnetics 14:
405-412, 1993
[19] Garcia-Sancho, J., Montero, M., et al.,
“Effects of Extremely Low Frequency
Electromagnetic Fields on Ion Transport in
Several Mammalian Cells.”
Bioelectromagnetics 15 : 579-588, 1994
[20] Graham, C., Cook, M.R., Riffle, D.W.,
“Human Melatonin During Continuous
Magnetic Field Exposure.”
Bioelectromagnetics 18 : 166-171, 1996
[21] Lin, R.S.; Dischinger, P.C.; Conde, J.,
Farrell, K.P. “Occupational exposure to
electromagnetic fields and the occurrence of
brain tumors. An analysis of possible
associations.” J. Occup Med. 27: 413-419;
1985.
[22] Preston-Martin, S.; Mack, W.; Henderson,
B.E., “Risk factors for gliomas and
meningiomas in males in Los Angeles
County,” Cancer Res. 49: 6137-6143; 1989.
[23] Bastuji-garin, S.; Richardson, S.; Zittoun,
R., “Acute leukaemia in workers exposed to
electromagnetic fields.” Eur. J. Cancer. 26:
1119-1120; 1990.
[24] Canseven, A.G., Seyhan, N., Mirshahidi,
S., Imir, T., “Suppression of Natural Killer
Cell Activity on Candida Stellatoidea by a
50 Hz Magnetic Field.” Electromagnetic
Biology and Medicine, 25 (2) : 79-85, 2006
[25] Seyhan N., Canseven A. G. & Güler G.,
“Animal Studies on the Effects of ELF and
Static EMF.” In Ayrapetyan S.N., Markov
M.S., eds. Bioelectromagnetics Current
Concepts, The Mechanisms of the Biological
Effect of Extremely High Power Pulses .
NATO Security through Science Series B:
Physics and Biophysics, Vol. 5, pp: 195-212,
2006
[26] Canseven, A.G., Seyhan, N., et al.,
“Extremely Low Frequency Electromagnetic
Field Effect on Brain Tissue and Blood
Plasma Electrolytes.” Med & Biol Eng &
Comput 37 (Suppl. 2) : 1336-1337, 1999
[27] Canseven A.G., Seyhan N., Aydın A.,
Çevik C., Işımer A., “Effects of Ambient
ELF Magnetic Fields : Variations in
Electrolytes Levels of Brain and Blood
Plasma.” Gazi Medical Journal 16 : 121 –
127, 2005
[28] Yokus, B.; Cakir, D. U.; Akdag, M. Z.,
Sert, C.; Mete, N., “Oxidative DNA damage
in rats exposed to extremely low frequency
electromagnetic fields.” Free Radical Res.
39: 317-323; 2005.
[29] Byus, C.V., Pieper, S.E., Adey, R., “The
effects of low-energy 60 Hz environmental
electromagnetic fields upon the growth
related enzyme ornithine decarboxylase.”
Carcinogenesis 8 : 1385-1389, 1987
[30] Wertheimer, N.; Savitz, D.A.; Leeper, E.,
“Childhood cancer in relation to indicators of
magnetic fields from ground current
sources.” Bioelectromagnetics 16: 86-
96;1995.
[31] Hakansson, N.; Floderus, B.; Gustavsson,
P.; Johansen, C.; Olsen J.H., “Cancer
incidence and magnetic field exposure in
industries using resistance welding in
welding in Sweden.” Occup. Environ. Med.
59: 481-486; 2002
[32] WHO Fact Sheet N° 263. Electromagnetic
Fields and Public Health - Extremely Low
Frequency Fields and Cancer, October 2001.
Modeling Elf Electromagnetic Field Effects On Skin’s Hydroxyproline Level
Using Neural Networks
Ayşe G. CANSEVEN, Gülay TOHUMOGLU, Abdükadir ÇEVİK, Nesrin SEYHAN
449
(http:// www.who.int/docstore/pehemf/
publications/facts_press/efact/efs263.htm
l) .
[33] IARC Monographs On The Evaluation Of
Carcinogenic Risks To Human Non-Ionizing
Radiation. Part 1 : Static and Extremely Low
Frequency (ELF) Electric and Magnetic
Fields. IARCPress, France, Lyon: Vol. 80,
2002
[34] Lai, H.; Singh, NP., “Magnetic fieldinduced
DNA strand breaks in brain cells of
the rat.” Environmental Health Perspectives.
112: 687-694; 2004.
[35] Singh, L P.; Lai, H., “60- Hz magnetic
field exposure induces DNA crosslink in rat
brain cells.” Mutat Res., 400: 313-320; 1998.
[36] Brocklehurst, B.; Mclauchlan, K.A., “Free
radical mechanism for the effects of
environmental electromagnetic fields on
biological systems.” Int J Radia. Biol. 69: 3-
24; 1996.
[37] Foulds IS, Barker AT., “Human Skin
Battery Potentials and Their Possible Role in
Wound Healing.” British J. Dermatology
109: 515-522, 1983.
[38] Bhagavan N.V., Medical Biochemistry,
Boston : Jones and Bartlett Publishers Inc,
1992.
[39] Ahmadian S., Zarchi S.R, Bolouri B.,
“Effects of extremely low frequency pulsed
electromagnetic fields on collagen synthesis
in rat skin.” Biotechnol Appl Biochem 43, 71-
75, 2006
[40] Guler G., Hardalac F., and Arıcıoglu A.,
“Examination of Electric Field Effects on
Lipid Peroxidation and Antioxidant Enzymes
by Using Multilayer Perceptron Neural
Network,” G. U. Journal Science, 18, pp. 27-
37, 2005.
[41] Guler G., Hardalac F., and Arıcıoglu A.,
“Examination of Electric Field Effects on
Tissues By Using Back Propagation Neural
Network,” Journal of Medical Systems 29:
679-708, 2005.
[42] Guler G., and Hardalac F., “Examination
of Electric field effects on oxidant and
antioxidant enzymes by using hybrid genetic
algoritm and neural network,” IFMBE Proc
3rd European Medical&Biological
Engineering Conference - EMBEC´05.
Prague, Czech Republic, vol. 11, pp: 1220-
1224, Nov. 20-25, 2005
[43] Canseven A.G., Seyhan N., “Design,
Installation and Standardization of
Homogenous Magnetic Field Systems For
Experimental Animals.” The 3rd European
Medical and Biological Engineering
Conference EMBEC'05, Prague, Czech
Republic, 20-25 November 2005
[44] Woessner JF., “The Determination of
Hydroxyproline in Tissue and Protein
Samples Containing Small Proportions of
This Iminoacid.” Arch Biochem Biophys 93 :
240-247, 1961.
[45] Hecht-Nielsen, R., Neurocomputing,
Addison-Wesley, Reading, MA.,1990
[46] Rumelhart, D.E, Hinton, G.E., Williams,
R.J., “Learning internal representation by
error propagation.” In: Rumelhart, D.E.,
McClleland, J.L. (Eds.). Parallel Distributed
Processing: Exploration in the
Microstructure of Cognition, Vol. 1. MIT
Press, Cambridge, MA, Chapter 8., 1986
[47] Cevik, A., A new approach for
elostoplastic analysis of structures:Neural
networks. Ph. D. Thesis, University of
Gaziantep, 2006
[48] Guzelbey I.H., Cevik A. and Gögüş M.T.,
“Prediction of rotation capacity of wide
flange beams using neural networks,”
Journal of Constructional Steel Research,
Vol. 62 (10), pp. 950-96, 2006
[49] Cevik A. and Guzelbey I.H., “A soft
computing based approach for the prediction
of ultimate strength of metal plates in
compression,” Engineering Structures, In
Press, Available online 30 June 2006.