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Orta ve Ağır Obstrüktif Uyku Apne Sendromu (OUAS) Olgularında PAP (Positive Airway Pressure) Titrasyonuna Objektif ve Subjektif Yanıtın Değerlendirilmesi”

“Objective and Subjective Responses to PAP (Positive Airway Titration) in Moderate and Severe Obstructive Sleep Apnea Syndrome”

Journal Name:

  • Maltepe Tıp Dergisi

Publication Year:

  • 2009

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Aim: The purpose of this study was to compare the objective and subjective responses of moderate and severe OSAS patients to the fi rst night polysomnography and PAP titration test. Materials and methods: Ten female, 26 male a total 36 patients with a mean age of 54 ± 11 years (range 32-73) and polysomnographically verifi ed as moderate and severe OSAS in Sleep Resarch Laboratory of Chest Diseases Department at Maltepe University Hospital between May 2008-May 2009 were included in the study. Subjective responses were obtained from the questionnaire applied on the morning after the fi rst polysomnography and PAP titration nights. Objective responses were also achieved from the polysomnographyrecordsof bothtest nights. We compared theobjectiveand subjective responses of patients to both tests. Diff erencesbetweenthetwo testsnights were evaulatedseperately. Visual analog scoring(VAS) wasused to evaluate subjective values. Results: When wecompared theresponsestothefi rst night polysomnographyandPAPtitrationwefoundstatisticallysignifi cant diff erences betwen the values of totalsleeptime, REMsleep, respiratoyarousals, basaloxygen saturation andminimalavarageoxygen saturation. Subjectiveresponsesrevealed that there were diff erences between the titration night and fi rst polysomnography nightsuggesting positivechanges in termsof patientsatisfaction andstatisticallysignifi cant diff erenceswere achieved betweenthetwonights regardingpatientsatisfaction of sleepqualityandfeelingof awaked rested in the morning (p<0.001). Conclusion: In moderate and severe OSAS cases we observed favorable effectsin patients responsesbothin objectiveandsubjectiveparameters on the fi rst nightof PAPexperiencecompared tothefi rst polysomnography night.
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Abstract (Original Language): 
Amaç: Bu çalışmada orta ve ağır obstrüktif uyku apne sendromu (OUAS) tanısı alıp PAP (Positive Airway Pressure) titrasyonuna alınan olguların, titrasyon gecesindeelde edilen objektif vesubjektifyanıtlarıileilkgeceyapılan polisomnografi testi yanıtları karşılaştırılmıştır. Yöntem: Maltepe Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Uyku Bozuklukları Laboratuvarında Mayıs 2008-Mayıs 2009 tarihleri arasında orta ve ağır OUAS tanısı almış olan erişkin, yaş ortalaması 54 ± 11 yıl (32-73 yaş arası), 10 kadın ve 26 erkek toplam 36 olgu çalışmaya alındı. Uyku laboratuvarındapolisomnografi testinealınan tümolgulara testin sonlandığısabahuygulanananketformundaki bilgiler kullanılarak, subjektif yanıtlar, polisomnografi kayıtlarındaki verilerden iseobjektifyanıtlarelde edildi. İlk test gecesi, titrasyon gecesi ile objektif ve subjektif veriler kullanılarak karşılaştırıldı. Subjektif verilerin değerlendirilmesinde vizüel analog skorlama (VAS) yöntemi kullanıldı. Bulgular: İlk gece PSG sonuçları titrasyon gecesi sonuçları ile karşılaştırıldığında; toplam uyku süresi, REMperiyodu, solunumsal arousallar, bazaloksijen satürasyonuveen düşükoksijensatürasyonudeğerlerinde; hastalarınsubjektifyanıtlarıdeğerlendirildiğinde ise, titrasyongecesindeilkgeceyanıtlarına göre herzamankiuykusuilekarşılaştırıldığında uyku memnuniyetialgısında, dinlenmişveuykusunualmışolarak uyanma algısındaolumluyöndeanlamlı farklılıklar elde edildi (p<0.001). Sonuç: Orta ve ağır OUAS grubunda ilk gece PAP uygulaması ile hem objektif hemsubjektifverilerdehastaalgı düzeyindeileriderecede anlamlıdüzelmeler kaydedilmiştir.
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REFERENCES

References: 

1. White DP. Sleep apnea. Proc Am Thorac Soc
2006;3.124–128.
2. Friedlander A.H, Walker L.A, Friedlander I.K. Diagnosing
and comanaging patients with obstructive sleep
apnea syndrome. JADA 2000; 131: 1178-1184.
3. Mc Nicholas WT. Diagnosis of obstructive sleep
apnea in adults. Proc Am Thorac Soc 2008; 5:154-
160.
4. Piper A J, Sullivan CE. Eff ects of short- term NIPPV
in the treatment of patients with severe obstructive sleep
apnea and hypercapnia. Chest 1994;105:434-440.
5. Kushida CA, Chediak A, Berry RB, Brown LK,
Gozal D, Iber C et al. Clinical guidelines for the manual
titration of Positive Airway Pressue in patients with
obstructive sleep apnea . Positive airway titration task
force of the American Academy of Sleep Medicine. J
Clin Sleep Med 2008; 4:157-171.
6. Morgenthaler TI, Aurora RN, Brown T, Zak R,
Alessi C, Boehlecke B et al. Practice parameters for the
use of autotitrating continuous positive airway pressure
devices for titrating pressures and treating adult patients
with obstructive sleep apnea syndrome: An update for
2007. An AASM Report .Sleep 2008;31:141-147.
7. Kakkar RK, Berry RB. Positive airway pressure
treatment for obstructive sleep apnea. Chest 2007;
132:1057-1072.
8. Bousculet LT, Vargas MSM, Maldonado AC, Zuniga
MR, Padilla RP.Autoadjusting positive pressure trial in
adults with sleep apnea assessed by a simplified diagnostic
approach. J Clin Sleep Med 2008 ;4:341-347.
9. Mansfield D, Naughton MT. Obstructive sleep
apnoea, congestive heart failure and cardiovascular
disease. Heart Lung and Circulation 2005;14S:S2–S7.
10. Quan SF, Gersh BJ. Cardiovascular consequences
of sleep-disordered breathing: Past, present and future.
Circulation 2004; 109: 951-957.
11. Gould D.Visual Analog Score (VAS).J Clin Nursing
2001;10:697-706.
12. Rechtschaff en A, Kales A: A manual of standardized
terminology, techniques and scoring system
for sleep satges in human subjects. Brain Information
Service: Los Angeles, UCLA, 1968.
13. American Academy of Sleep Medicine. Sleep-related
breathing disorders in adults: recommendations
for syndrome definition and measurement techniques
in clinical research; The Report of an AASM Task Force.
Sleep 1999;22:667-689.
14. Ballard RD, Gay PC, Strollo PJ. Interventions to
improve compliance in sleep apnea patients previously
non-compliant with continuous positive airway pressure.
J Clin Sleep Med 2007;3:706-712.
15. Kushida CA, Littner MR, Hirshkowitz M, Morgenthaler
TI, Alessi CA, Bailey D et al. Practice parameters
for the use of continuous and bilevel positive airway
pressure devices to treat adult patients with sleeprelated
breathing disorders.An American Academy of
Sleep Medicine Report.Practice parameters for CPAP
and Bilevel PAP. Sleep 2006;29: 375-380.
16. Weaver TE, Mailsin G, Dinges DF, Bloxham T,
George CFP, Greenberg H et al. Relationship between
hours of CPAP use and achieving normal levels of sleepiness
and daily functioning. Sleep 2007;30: 711-719.
17. Fidan F, Ünlü M, Sezer M, Geçici Ö, Kara Z. Uyku
apne sendromlu hastalarda CPAP tedavisine uyum ve
tedavinin anksiyete ve depresyon üzerine etkisi. Tüberküloz
ve Toraks Dergisi 2007; 55 (3):271-277.
18. Mulgrew AT, Cheema R, Fleetham J, Ryan F, Ayas
NT. Eff icacy and patient satisfaction with autoadjusting
CPAP with variable expiratory pressure vs standard
CPAP: a two-night randomized crossover trial. Sleep
Breath 2007;11:31-37.
19. Mc Nicholas WT. Compliance with nasal CPAP
therapy with obstructive sleep apnoea:how much is
enough? Eur Respir J 1997;10:969-970.
20. Schwartz DJ, Karatinos G. For Individuals with
obstructive sleep apnea, Institution of CPAP therapy
is associated with an amelioration of symptoms of
depression which is sustained long term. J Clin Sleep
Med 2007;3:631-635.

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