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C vitamini Uygulamalı Kısıtlı Gıda Alınımının Bazı Dokuların C vitamini Düzeylerine Etkisi

The Effect of Limited Food Intake with Vitamin C Application on the Some Tissues Vitamin C Levels

Journal Name:

  • Maltepe Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: The present work investigated the effect of limited food intake on some tissues vitamin C levels and the role of vitamin C application to this effect. Methods: The animals receiving vitamin C treatment were given vitamin C by a single dose (500 mg kg-1body weight) intraperitoneally before periods of limited food intake lasting24,48 and 120 hours. Application to animals without vitamin C in 24 hours, 48 hours and 120 hours were limited diet. Results: The results indicated that limited food intake decreased blood vitamin C level. An application-induced increase was observed in the blood vitamin C levels of the animals which received vitamin C application prior to limited food intake periods. Brain vitamin C level increased especially during 120 hour and 48 hour limited food intake, and in 24 hour and 48 hour limited food intake after vitamin C treatment. Liver vitamin C level significantly increased in 24 hour and 48 hour limited food intake after vitamin C treatment. Conclusion: We conclude that limited food intake period is important for brain vitamin C levels, and limited food intake period with vitamin C is important for liver vitamin C levels
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Abstract (Original Language): 
Amaç: Sınırlı miktarda besin alınımının doku C vitamini düzeyine etkisi ve bu etkiye C vitamini ilavesinin rolünü araş-tırmaktır. Gereç ve Yöntem: Çalışmamızda C vitamini uygulama¬sı, sınırlı besin alımlarının öncesinde tek doz (500 mg/kg, i.p.) yapılmıştır. Çalışmamız C vitamini uygulamalı, 24 saat, 48 saat ve 120 saat sürelerde sınırlı besin verilen kobaylarda ve C vitamini uygulaması yapılmayan 24 saat, 48 saat ve 120 saat süreler de sınırlı besin verilen kobaylarda yapılmıştır. Bulgular: Sonuçlarımız sınırlı besin alınımında kan C vi-tamini düzeyinin azaldığını gösterdi. Sınırlı besin alınımında C vitamini uygulaması ile kan C vitamini düzeyi yükseldi. Be¬yin dokusu C vitamini düzeyi özellikle 120 saat ve 48 saat sü¬relerle sınırlı besin alınımında yükselirken C vitamini uygula¬ması yapıldığında 48 saat ve 24 saat süreli sınırlı besin alımın¬da yükseldiği gözlendi. Karaciğer C vitamini düzeyi ise 24 sa¬at ve 48 saat süre ile sınırlı besin alınımı öncesinde C vitami¬ni uygulanan deneklerde belirgin olarak yükselmiştir. Sonuç: Çalışmamız göstermiştir ki sınırlı besin alımında¬ki değişen süreler özellikle beyin dokusu C vitamini düzeyi için önemlidir. C vitamini uygulaması yapılan sınırlı besin alı¬mındaki değişen süreler ise karaciğer dokusu C vitamini dü¬zeyi için önemlidir.
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