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BAZI PİRAZOL-3-KARBOKSİLİK ASİTLERİN ÇEŞİTLİ DİAMİN VE DİOLLERLE REAKSİYONLARININ İNCELENMESİ

THE INVESTIGATION OF THE REACTIONS OF SOME PYRAZOLE-3-CARBOXYLIC ACIDS WITH VARIOUS DIAMINES AND DIOLS

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Abstract (2. Language): 
In this study, some new derivatives were synthesized of 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (1) and 4-(ethoxycarbonyl)-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (2) that they were pyrazole carboxylic acid derivatives. Firstly, 1 and 2 reacted with SOCl2 to transform them into acyl chlorides (3, 4). Then various bis-carboxamide derivatives (5–8) were obtained from the reaction of 3 and 4 with various diamines and also a β-hydroxy ester (9) derivative was obtained from the reaction of 3 with ethylene glycol. The structures of synthesized compounds were elucidated with using FT-IR, 1H NMR, 13C NMR and elemental analysis methods.
Abstract (Original Language): 
Bu çalışmada pirazol karboksilik asit türevleri olan 4-benzoil-1-(3-nitrofenil)-5-fenil-1H-pirazol-3-karboksilik asit (1) ve 4-(etoksikarbonil)-1-(3-nitrofenil)-5-fenil-1H-pirazol-3-karboksilik asit (2) bileşiklerinin bazı yeni türevleri sentezlendi. Öncelikle 1 ve 2 bileşikleri SOCl2 ile etkileştirilerek açil klorürlerine (3, 4) dönüştürüldü. 3 ve 4’ün çeşitli diaminlerle reaksiyonlarından yeni bis-karboksamit türevlerine (5–8) geçildi. Ayrıca 3’ün etilen glikol ile reaksiyonundan ise bir β-hidroksi ester türevi (9) elde edildi. FT-IR, 1H NMR, 13C NMR ve elementel analiz yöntemleri kullanılarak sentezlenen bileşiklerin yapıları aydınlatıldı.
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