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50 Hz frekanslı manyetik alanın ratlarda oluşturduğu histopatolojik değişiklikler

The hisiopathological changes in the rats caused by magnetic field of 50 Hz. frequency.

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2002

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Background: Electromagnetic fields (EMF) are the most important environment problems that effect the public health in our century. Increasing incidence of coronary heart disease, leukemia, lymphoma, and Alzheimer in the patients who are effected from magnetic fields, are revealing that these sources can not be used unlimitedly. İn this study, we vvould like to investigate the effect of hairdryer on the rats. Materials and methods: İn this study, 200-250 gr weighted 29 male rats were used. 15 of them were control group, and 14 were faced with EMF. A BKK 1161 SK hairdryer was used as the magnetic field source. This machine had 600 Watt (W) povver, 220 V - 50 Hz resistance, and a mean magnetic field counted 100-150 mG. The distance between the subjects and the machine was 20-25 cm. EMF was performed on them for 3 days of each week, and 5 minutes of each day, and it was lasted after 3 months with a total period of 205 minutes. At the end the malondialdehid (MDA) levels in the subjects sera were calculated, and they were sacrificed and their cerebrum, thymus, lungs, heart and great vessels, liver, kidneys, and spleen were taken to histopathologic examination under üght microscope. Results: İt was obviously observed that the EMF in 50 Hz frequency increases the mononuclear celi infiltration in the viscera; especially, it was estimated that EMF causes alveolar desîruction in the lungs, tubuler degeneration in the kidneys, glial proliferation in the cerebrum, fibrosis in the liver, and adventitial mononuclear celi infiltration in the great vessels in 3 months, vvhich is thought to be a very short period. Statistically, the subendothelıal dissection in the great vessels was not found significant, however, this was thought to be an imponant finding. The serum MDA levels of EMF group was increased, but statistically, this was not significant. Conclusion: We concluded that EMF causes an increase in the production of free oxygene radicals, and İn the late-term this results with vahous diseases including cancers and atherccclerotic diseases.
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Abstract (Original Language): 
Amaç: Günümüz toplumunda sağlığımızı tehdit eden elektromanyetik alanlar (EMA), en önemli çevre problemleridir. Manyetik alana maruz kalanlarda koroner kalp hastalığı, lösemi, lenfoma ve Alzheimer hastalığının görülme sıklığındaki artışlar bu kaynakların sınırsız kullanılamayacağını hatırlatmaktadır. Günlük konforumuzu artıran ev aletlerinden saç kurutma makinasının ratlardaki etkisini araştırmayı amaçladık. Materyal ve metod: Çalışmada 200-250 gr ağırlığında 29 erkek rat kullanıldı. Bunların 15' i kontrol grubunu oluştururken, 14' ü EM A' a maruz bırakıldı. Manyetik alan kaynağı olarak BKK 1161 SK saç kurutma makinası kullanıldı. Cihaz 600 Watt (W) lık güce, 220 V - 50 Hz' tık gerilime ve ortalama 100-150 mG' luk manyetik alana sahipti. Deneklerle makine arasında ortalama 20-25 cm' İlk mesafeden haftada 3 gün, her seferinde 5 dakika olmak üzere toplam 3 ay boyunca 205 dakika uygulandı. Bu sürenin sonunda: serum malondialdehit (MDA) düzeyleri ile beraber beyin, timus, akciğer, kalp ve büyük damarlar, karaciğer, dalak ve böbrek eksize edilip ışık mikroskobunda histopatolojik olarak değerlendirmeye alındı. Sonuçtan 50 Hz frekanslı manyetik alanın organlarda iltihabı hücre infiltrasyonunu belirgin şekilde artırdığı; özellikle akciğerlerde alveoler harabiyeii. böbreklerde tübüler dejenerasyonu, beyinde glial prolıferasyonu, karaciğerde fibrozisi, büyük damarlarda adventisyal iitihabi infiltrasyonu üç ay gibi bir sürede oluşturduğu tesbit edildi. Büyük vasküler yatakta subendotelyal ayrılmayı, istatistiki bir değere sahip olmamakla beraber önemli bir bulgu olarak düşünmekteyiz. Serum MDA değerleri manyetik alanda kısmi artış gösterirken istatistiki olarak anlamlı değildi. Karar: EMA' nın serbest oksijen radikallerinin üretimini artırarak uzun dönemde kanserden aterosklerotik hastalıklara kadar farklı patolojilere yol açabileceğini düşünmekteyiz.
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