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Migren hastalarında trigeminoservikal refleks: Ön çalışma

Trigemino-cervical reflex in patients with migraine

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Abstract (2. Language): 
Neurophysiological studies have shown decreased excitabiüty of the brain stem inhibitory interneurons in patients with headache. The C3 component of the trigemino-cervical reflex is nociceptive İn character and may reflect the brain stem interneuron activity. This ref!ex is evoked by stimulation of the supraorbital nerve and recorded from the neck muscles. We recorded this reflex in 16 patients with migraine vvithout aura and in 20 healthy subjects. There was not significant difference in latencies and ampiitudes between the two groups. We concluded that there İs not decrease in brain stem inhibitory interneuronal activity in migraine and this mechanism may not be responsible from pain control.
Abstract (Original Language): 
Nörofizyolojik çalışmalar başağnsı olan hastalarda beyinsapı inhibltör nöronlarda uyarılabilirliğin azaldığını göster¬miştir. Trigeminoservikal refleksin C3 komponenti nosiseptif karakterdedir ve beyin sapındaki nöronlar arası aktiviteyi yansıtabilir. Bu refleks supraorbital sinirin stimulasyonu ile boyun kaslarından kaydedilir. Bizim çalışmamızda 16 aurasız migrenii, 20 normal kişide trigeminoservikal refleks kaydedildi. Latans ve amplitüd ölçümlerinde iki grup arasında anlamlı bir fark bulunmadı. Bu sonuç bize migrenlilerde beyinsapı inhibitör nörona! aktivitede azalma olmadığını ve bu mekanizmanın ağrıdan sorumlu olamayacağını düşündürdü
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