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PEDİATRİK OLGULARDAN İZOLE EDİLEN 3 KLUYVERA SUSUNUN DEĞERLENDİRİLMESİ

EVALUATION OF THREE KLUYVERA STRAİNS ISOLATED FROM PEDIATRICS CASES

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Abstract (2. Language): 
Aim: Kluyvera sp., a Gram-negative bacterium in Enterobacteriaceae family, may give rise to such infections as urinary system infections, enteritis, soft tissue infections and sepsis in children. It is known that Kluyvera species is an opportunistic pathogen detected in immunosuppressed hosts as well as in immunocompetent ones. Considering that it may enlight future studies related to Kluyvera infections, studies in the literature have been scanned. Material and Method: The data about Kluyvera spp. isolates were obtained retrospectively from clinical microbiology records. Result: It was seen that, of the 3 Kluyvera isolates, 1 was a urine specimen, and the other 2 were from umbli- cal area. In this study, antimicrobial susceptibility studies of the clinically significant Kluyvera isolates showed susceptibility patterns similar to those reported in the medical literature, namely trends of resistance to ampicillin and first- and second-generation cephalosporins. Moreover none of the cli-nically significant isolates were resistant to amikacin, ciprofloxacin, gentamycin, and trimetho-prim+sulfametoxazole. Conclusion: It was concluded in the light of both the studies in the litera¬ture and this study that rare and opportunistic organisms, such as Kluyvera may be an infection cause in children.
Abstract (Original Language): 
Amaç: Enterobacteriaceae familyasında yer alan Gram negatif bir bakteri olan Kluyvera sp. çocuk¬larda üriner sistem infeksiyonları, enterit, yumuşak doku infeksiyonları ve sepsis gibi birçok infeksiy-ona sebep olabilmektedir. Kluyvera türlerinin immunsupresif hastalarda olduğu kadar immunkom-petanlar için de fırsatçı bir patojen olduğu bilinmektedir. Kluyvera infeksiyonları ile ilgili bundan sonra yapılacak olan çalışmalara ışık tutacağı düşünülerek Kluyvera hakkında yapılan literatür çalışmaları da gözden geçirilmiştir. Gereç ve Yöntem: Kluyvera izolat verileri klinik mikrobiyoloji kayıtlarının retro-spektif analizi ile elde edilmiştir. Bulgular: Retrospektif incelemede üç izolatın birinin idrar, ikisinin umblikal apse örneklerinden soyutlandığı saptandı. Çalışmada, klinik öneme sahip Kluyvera izolat-larının antibiyotik duyarlılıkları, (birinci ve ikinci kuşak sefolosporinler ve ampisiline karşı dirençli olmaları ile amikasin, siprofloksasin, gentamisin ve trimetroprim+sulfametoksazol'e duyarlılıkları) liter¬atürde rapor edilen paternlerle benzerlik gösterdi. Sonuç: Hem bizim verilerimiz hem de literatür bil¬gilerinin bir sonucu olarak Kluyvera gibi nadir ve fırsatçı organizmalar çocuklarda önemli infeksiyon etkeni olabileceği sonucuna varılmıştır.
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