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ÇOCUKLARDA PERİNE VE PERİÜRETRADAKİ AEROB BAKTERİ KOLONİZASYONU ÜZERİNE SACCHAROMYCESS BOULARDİİ'NİN ETKİSİ

THE EFFECT OF SACCHAROMYCESS BOULARDİİ ON AEROB BACTERIAL COLONIZATION İN PERİNE AND PERIURETRA IN CHILDREN

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Aim: This study was designed to evaluate whether Saccharomyces boulardii (S. boulardii ) is effec¬tive on the bacterial colonization of perineal and periurethral areas in children and could be useful in protective treatment in children with recurrent urinary tract infections. Material and method: Fifty four children were included the study. Perineal and periurethral area cultures provided from each of these children were inoculated into the aerobic cultures seperately. Having been orally given only a single dose of 250 mg S. Boulardii per day for ten days, cultures were repeated. Results: Having been administered S. Boulardii, the number of the cultures which yielded Escherichia coli in both perineal and periurethral areas were found to be decreased significantly. No other uropathogens such as Klebsiella and Proteus were detected to be decreased.Conclusion: This study showed that S. Boulardii administration could be useful in the prevention of urinary tract infection recurrences.
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Abstract (Original Language): 
Amaç: Bu çalışma çocuklarda perine ve periüretral bölgedeki bakteriyel kolonizasyon üzerine Saccharomyces boulardii (S. boulardiij'nin etkisini incelemek ve tekrarlayan idrar yolu enfeksiyonu (İYE) olan çocuklarda koruyucu tedavide yardımcı olup olamayacağını değerlendirmek amacıyla planlanmıştır. Gereç ve yöntem: Çalışmaya 54 çocuk alındı. Her birinden elde edilen perine ve pe¬riüretral bölge materyalleri ayrı ayrı aerob ortamda kültüre ekildi. Her çocuğa on gün süreyle ağızdan, günde tek doz 250 mg.S. boulardii içeren preparatın verilmesinden sonra kültürler tekrar-landı. Bulgular: S. boulardii verilmesinden sonra hem perine hem de periüretral bölgede Escherichia coli (E.colij'nin ürediği kültür sayısının anlamlı şekilde azaldığı bulundu. Diğer üropato-jenlerden Klebsiella ssp. ve Proteus ssp'de azalma tespit edilmedi. Sonuç: Bu çalışma İYE'nin tekrarının önlenmesinde S. boulardii'nin faydalı olabileceğini göstermektedir.
FULL TEXT (PDF): 
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  • 4
167-172
  • Turkish

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