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Down Sendromu Olan iki Yenidoğanda Konjenital Lösemi

Congenital Leukemia in Two Newborns with Down Syndrome

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Congenital Leukemia is rare disease seen at birth or in the first 4 weeks of life . The incidence of Congenital Leukemia is 1 over 4.7 million live births. Most of the cases are myeloblastic leukemia. Usually symptoms like leukocytosis, petechia, echymosis, cutaneous nodules, hepatosplenomegaly and central nervous system involvement are seen. Two newborns with Down syndrome which were septic at application and diagnosed as congenital leukemia are presented in this article. The early recognition of such cases and finding opportunity to treat before the appearance of secondary complications such as sepsis play an essential role for saving life.
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Abstract (Original Language): 
Konjenital lösemi, doğumda veya yaşamın ilk 4 haftasında ortaya çıkan nadir bir hastalıktır. Konjenital löseminin görülme sıklığı 4,7 milyon canlı doğumda 1’dir. Konjenital lösemilerin büyük çoğunluğu akut myeloblastik lösemidir. Genellikle lökositoz, peteşi, ekimoz, kutanöz nodüller, hepatosplenomegali ve santral sinir sistemi tutulumu şeklinde bulgular vermektedir. Bu yazımızda down sendromu olan, sepsis kliniği ile gelen ve yenidoğan döneminde konjenital lösemi tanısı konulan iki olgu sunulmuştur. Bu hastaların erken dönemde tanınması ve sepsis gibi ikincil klinik tablolarının ortaya çıkmadan tedavi şansının yakalanması hayat kurtarıcı rol oynamaktadır.
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  • 1
40-42
  • Turkish

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