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Multiple Organ Disfonksiyonu Sendromu ve mekanik ventilasyon

Multiple organ dysfunction syndromes and mechanic ventilation

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Abstract (2. Language): 
Systemic inflammatory response syndrome and multiple organ dysfunction syndromes (MODS) are common syndromes in intensive care unit. An effective method of preventing and treatment could not yet be found. High mortality rates could be decreased by early diagnosis and predictive treatment. It has been demonstrated that multiple organ dysfunction may occur with trauma, burn, shock, cardiac arrest, various non-bacterial infection and certain infectious focus. MODS generally follow a predictable course; typically acute respiratu-ar distress syndrome is the first. The most important and effective treatment is early diagnosis and eliminating the infectious focus. Early mechanic ventilation and dynamic supportive care should be applied for reduc¬ing the mortality and morbidity.
Abstract (Original Language): 
Sistemik inflamatuar cevap sendromu ve multiple organ disfonksiyonu sendromu (MODS) yoğun bakım ünitelerinde karşılaşılan ortak bir sendromdur. Etkili bir önleme ve tedavi yöntemi henüz bulunamamıştır. Yüksek mortalite oranları erken tanı ve koruyucu tedavi ile azaltılabilir. Multiple organ disfonksiyonun (MOD) travma, yanık, şok, kardiyak arrest, çeşitli non-bakteriyel enfeksiyonlar ve belirli enfeksiyon odakları ile ortaya çıkabildiği belirtilmiştir. Başlatıcı olay ne olursa olsun, MODS genellikle tahmin edilebilir bir yol izler; tipik olarak akut respiratuvar distres sendromu ilktir. En önemli ve etkili tedavi; erken tanı ve enfeksiy¬on odağının elimine edilmesidir. Mortalite ve morbiditeyi azaltmak için erken mekanik ventilasyon ve dinamik destekleyici bakım uygulanmalıdır.
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REFERENCES

References: 

1. Pietrantoni C, Minai OA, Yu NC, Maurer JR, Haug MT, Mehta AC, et al. Respiratory failure and sepsis are the major causes of ICU admissions and mortality in survivors of lung transplants. Chest. 2003 Feb;123(2):504-9.
2. Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ. Multiple organ dysfunction score: a reli¬able descriptor of a complex clinical outcome. Crit Care Med 1995: 23: 1638-52.
3. Barriere SL, Lowry SF. An overview of mortality risk pre¬diction in sepsis. Crit Care Med 1995: 23: 376-93.
4. Shoemaker WC. Circulatory mechanisms of shock and
their mediators. Crit Care Med 1987: 15: 787-94.
5. Shoemaker WC, Appel PL, Kram HB. Tissue oxygen debt as a determinant of postoperative organ failure. Prog Clin Biol Res. 1989;308:133-6.
6. Faist E, Baue AE, Dittmer H, Heberer G. Multiple organ failure in polytrauma patients. J Trauma 1983: 23: 775-87.
7. Fry DE, Pearlstein L, Fulton RL, Polk HC Jr. Multiple sys¬tem organ failure. The role of uncontrolled infection. Arch Surg 1980: 115:136-40.
8. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. Prognosis in acute organ system failure. Ann Surg. 1985:
202: 685-93.
9. Goris RJ, te Boekhorst TP, Nuytinck JK, Gimbrere JS. Multiple-organ failure. Generalized autodestructive inflam¬mation? Arch Surg 1985; 120: 1109-15.
10. Biffl WL, Moore EE. Splanchnic ischemia/reperfusion and multiple organ failure. Br J Anaesth 1996; 77 : 59-70.

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