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Çocukluk çağı idrar yolu enfeksiyonlarında Escherichia coli ve antibiyotik direnci

Escherichia coli and antibiotic resistance in childhood urinary tract infections

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2006

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Aim: Urınary tract infections and antibiotic resistance are still a major health problem in childhood. In this study we aimed to detect the antibiotic resistance in urinary tract infection with E. coli and changing ratio in antibiotic resistance by years. Method: We evaluated the microbiologic data of children with urinary tract infection retrospectively. Results: In two years, there were 132 children with community-acquired urinary tract infection by E. coli. Antibiotic resistance were detected as 79% to ampicilline, 63.2% to ampicilline-sulbactam, 53% to amoxicillin-klavunat, 82.2% co-trimoksazole, 6.6% to gentamycine, 10% to netilmycin, 11.5% to amikacin, 21.9% to cefuroxime and 6.8% to ceftriaxone. Antibiotic resistance significantly increased to co-trimoksazole (p<0.01), in three years. In conclusion, in childhood urinary tract infection, pathogen microorganism and antibiotic resistance sould be evaluated periodically. Antimicrobial chemotherapy must be considered with result of in vitro antibiotic susceptibility tests.
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Abstract (Original Language): 
Amaç: Çocukluk çağında idrar yolu enfeksiyonları ve antibiyotik direnci halen önemli bir sağlık sorunudur. Bu çalışmada E. coli ile gelişen idrar yolu enfeksiyonunda antibiyotik direncini ve yıllar içinde antibiyotik direncinde gelişen değişiklikleri ortaya çıkarmayı amaçladık. Yöntem: İdrar yolu enfeksiyonu olan çocukların mikrobiyolojik sonuçlarını retrospektif olarak değerlendirdik. Bulgular: İki yılda E. coli ile gelişen toplumdan kazanılmış idrar yolu enfeksiyonu olan 132 çocuk vardı. Ampisiline %79, ampisilin-sulbaktama %63.2, amoksisilin klavunata %53, ko-trimoksazole %82.2, gentamisine %6.6, netilmisine %10, amikasine %11.5, sefuroksime %21.9 ve seftriaksona %6.8 oranında direnç saptandı. Ko-trimoksazole karşı dirençte 3 yıl içinde anlamlı artış görüldü (p<0.01). Sonuç olarak çocukluk çağı idrar yolu enfeksiyonlarında periyodik olarak patojen mikroorganizmalar ve antibiyotik dirençleri değerlendirilmelidir. Antibiyotik tedavisi in vitro antibiyotik duyarlılık sonuçlarına göre kararlaştırılmalıdır.
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  • 2
12-16
  • Turkish

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