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Primer akciğer tümörlerinde prebronkoskopik ve postbronkoskopik balgam sitolojileri

Prebronchoscopic and postbronchoscopic sputum cytologies in primary lung tumors

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2008

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Purpose: To determine the utility of the sputum cytology in the evaluation of the primary lung tumors in our faculty by comparing the cytology results and histopathology results of patients who underwent bronchoscopy. Material and Method: We compared the prebronchoscopic and postbronchoscopic sputum cytology results and histopathology results of 64 patients who underwent bronchoscopy between 2002 and 2005 in Süleyman Demirel University School of Medicine. Cytology results were categorized as benign, suspicious for malignancy, malignant and insufficient. Results: The diagnosis of prebronchoscopic sputum cytology were benign, insufficient, suspicious for malignancy and malignant in 37(77.1%), 2(4.2%), 5(10.4%), 4(8.3%) cases respectively. Sensitivity, specificity, accuracy of the prebronchoscopic sputum cytology were 28.6%, 84.4%, 67.4% respectively. The diagnosis of postbronchoscopic sputum cytology were benign, insufficient, suspicious for malignancy and malignant in 32(76.2%), 3(7.2%), 6(14.2%), 1(2.4%) cases respectively. Sensitivity, specificity, accuracy of the prebronchoscopic sputum cytology were 29.2%, 100%, 56.4% respectively. Conclusion: Sputum cytology is a cheap and noninvazive diagnostic method for primary lung tumors.
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Abstract (Original Language): 
Amaç: Primer akciğer tümörü ön tanısıyla bronkoskopi yapılarak biyopsi alınan olguların prebronkoskopik ve postbronkoskopik balgam sitolojisi sonuçlarını histopatoloji sonuçlarıyla karşılaştırarak fakültemizde balgam sitolojilerinin etkinliğinin araştırılması. Materyal ve Metod: SDÜ Tıp pakültesinde 2002-2005 yılları arasında bronkoskopi yapılarak biyopsi alınan 64 hastaya ait prebronkoskopik ve/veya postbronkoskopik balgam sitolojisi sonuçları histopatoloji sonuçlarıyla karşılaştırıldı. Sitoloji sonuçları benign, malignite kuşkulu, malign ve yetersiz olarak sınıflandırıldı. Bulgular: İncelenen 48 adet prebronkoskopik balgam örneğinin 37'si (%77.1) benign, 2'si (%4.2) yetersiz, 5'i (%10.4) malignite kuşkulu, 4'ü (%8.3) malign olarak rapor edilmiştir. Prebronkoskopik balgam sitolojisinin duyarlılığı %28.6, özgüllüğü %84.4, tanı değeri %67.4'dür. İncelenen 42 adet postbronkoskopik balgam örneğinden 32'si (%76.2) benign, 3'ü (%7.2) yetersiz, 6'sı malignite kuşkulu (%14.2), 1'i (%2.4) malign olarak rapor edilmiştir. Postbronkoskopik balgam sitolojisinin duyarlılığı %29.2, özgüllüğü %100, tanı değeri %56.4'dür. Sonuç: Balgam sitolojisi primer akciğer tümörlerinde ucuz ve noninvaziv bir tanı yöntemidir.
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  • 1
12-16
  • Turkish

REFERENCES

References: 

1.
Lope
z A. The lung cancer epidemic in developed countries. In: Lopez AD, Caselli G, Valkonen T. Adult mortality in developed countries: from description to explanation. Oxford, OxfordUniversityPress, l995; lll-l34.
2. Ries LAG. Influence ofextent ofdisease, histology and demographic factors on lung cancer survival in the SEER population-based data. Semin Surg Oncol l994;l0:2l-30.
3. Wilde J.Al0 year follow-up ofsemi-annual screening
for early detection oflung cancer in the Erfurt County, GDR. Eur Respir J l989;2:656-662.
4. Fontana RS, Sanderson DR, Woolner LB, et al. Screening for lung cancer. A critique ofthe Mayo Lung project. Cancer l99l;67:ll55-ll64.
5. Rivera MP, Detterbeck F, Mehta AC. Diagnosis of Lung Cancer The Guidelines.Chest 2003; l23:l29S-l36S.
6. Jack CIA, Sheard JDH, Lippitt B, et al. Lung cancer in elderly patients: the role ofinduced sputum production to obtain a cytological diagnosis. Age and Aging l993;22:227-229.
7. Khajotia RR, Mohn A, Schalleschak J, et al. Induced sputum and cytological diagnosis oflung cancer. Lancet l99l;338:976-977.
8.
Yükseko
l İ, Balkan A, Özkan M, Şevketbeyoğlu H, Bilgiç H, Ekiz K, Demirci N, Seber O. Periferik akciğer kanserlerinin tanısında bronkoskopik lavaj, bronş biyopsisi ve postbronkoskopik balgam sitolojisinin tanı değeri. Tüberküloz ve Toraks Dergisi 2003;5l:258-
264.
9. Tockman MS, Mulshine JL. Sputum screening by quantitative microscopy: a new dawn for detection of lung cancer? Mayo Clin Proc l997;72:788-90.
10. Midthun DF, Jett JR. Lung tumors. In: Albert RK, Spiro SG. Comprehensive Respiratory Medicine. London, Harcourt Brace and Company Limited, l999;
843-927.
11. Bach PB, Kelley MJ, Tate RC, McCrory DC. Screening for Lung Cancer A Review ofthe Current Literature.
S.D.Ü. Tıp pak.
Derg
. 2008:15(1)/ 12-16
16
Bozkurt, Prebronkoskopik ve postbronkoskopik balgam sitolojileri
Chest2003;l23:72S-82S.
12. Mehta
AC
, Marty JJ, Lee FYW. Sputum cytology in lung cancer. Clin Chest Med l993;l4:69-85.
13. Gilbert S, Douglas CM. Performance characteristics ofdifferentmodalities for diagnosis of suspected lung cancer : Summary ofpublished evidence. Chest 2003; l23: ll5-l28.
14. Koss LG. Tumors ofthe Lung: Conventional Cytology and Aspiration Biopsy. In: Koss LG. Diagnostic CytologyVol:l, (4th Ed) Philadelphia, J.B. Lippincott Comp, l992;849-855.

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