Buradasınız

Koroner arter anevrizmalı hastaların anjiyografik ve klinik özellikleri: 52 hastanın retrospektif incelenmesi ve literatürün gözden geçirilmesi

Angiographic and clinical characteristics of patients with coronary artery aneurysm: A retrospective analysis of 54 patients and review of the literature

Journal Name:

Publication Year:

Abstract (2. Language): 
Aim: Coronary artery aneurysm (CAA) is a rare type of coronary artery disease. There is a lack of literature data about the clinical characteristics and long term prognosis of patients with CAA. In this study; we aimed to investigate frequency, angiographic and clinical characteristics of patients with CAA. Methods: Clinical characteristics and coronary angiograms of 52 patients who were diagnosed as having CAA between January 2000 and November 2004 were investigated. Results: Total 6842 patients underwent coronary angiography and fifty two of them 39 male (75%), 13 female (25%) were diagnosed as having CAA (%0.76). CAA was mostly seen in left anterior descending artery (n=22, %42). Hypertension was the most frequent atherosclerotic risk factor (n=32,61%). Stenotic coronary artery disease accompanying to the CAA was present in 34 (65%) patients. Conclusions: In our study, frequency of CAA was % 0.76. Hypertension was the most frequent risk factor and left anterior descending was the most common site of aneurysm. purthermore, presence of stenotic coronary artery disease with CAA was common.
Abstract (Original Language): 
Amaç: Koroner arter anevrizması, koroner arter hastalığının nadir rastlanan bir türüdür. Koroner anevrizmalı hastaların klinik özellikleri ve uzun dönem prognozlarına dair literatür bilgisi azdır. Bu çalışmada; koroner arter anevrizmalı hastaların sıklığını, klinik ve anjiyografik özelliklerini incelemeyi amaçladık. Gereç ve Yöntem: Kliniğimizde Ocak 2000 ile Kasım 2004 tarihleri arasında anjiyografik olarak koroner arter anevrizması tespit edilen 52 hastanın klinik özellikleri ve anjiyogramları incelendi. Bulgular: Koroner anjiyografi yapılan 6842 hastanın 52'sinde (%0.76) koroner arter anevrizması vardı 39 erkek (%75), 13 kadın (%25). Koroner arter anevrizması en sık sol ön inen arterde (n=22, %42) tespit edildi. Hipertansiyon (n=32, %61) en sık görülen aterosklerotik risk faktörüydü. Koroner arter anevrizmasına eşlik eden tıkayıcı koroner arter hastalığına 34 hastada (%65) rastlandı. Sonuç: Çalışmamızda koroner arter anevrizması sıklığı %0.76 idi. Koroner arter anevrizmasına en sık sol ön inen arterde rastlanmış olup bu hastalarda hipertansiyon en sık karşılaşılan risk faktörüdür. Koroner arter anevrizması ile tıkayıcı koroner arter hastalığı birlikteliğine sık rastlanmaktadır.
1-5

REFERENCES

References: 

1. Falsetti HL, Carrol RJ. Coronary artery aneurysm. Chest 1976;69:630-6.
2. Befeler B, Aranda MJ, Embi A, Mullin FL, El-Sherif N, Lazzara R. Coronary artery aneurysms: study ofthe etiology, clinical cource and effect on left ventricular function and prognosis. Am J Med 1977;62:597-607.
3. Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp HG, et al. Aneurysmal coronary artery disease. Circulation 1983;67:134-8.
S.D.Ü. Tıp pak.
Derg
. 2008:15(4)/1-5
Acar, Koroner arter anevrizmaları
5
4. Hartnell GG, Parnell BM, Pridie RB. Coronary artery ectasia. Its prevalence and clinical significance in 4993 patient. Br Heart J 1985;54:392-5.
5. Markis JE, Joffe CD, Cohn PF, Feen DJ, Herman MV, Gorlin R. Clinical significance of coronary arterial ectasia. Am J Cardiol 1976;37:217-22.
6. Wang KY, Ting CT, St John Sutton M, Chen YT. Coronary artery aneurysms: A 25-patient study. Cathet Cardiovasc Intervent 1999;48:31-8.
7. Syed M, Lesch M. Coronary artery aneurysm: a review. Prog Cardiovasc Dis 1997;40:77-84.
8. Kruger D, Stierle U, Herrmann G, Simon R, Sheikhzadeh A. Exercise-induced myocardial ischemia in isolated coronary artery ectasias and aneurysms ("dilated coronopathy"). J Am Coll Cardiol 1999;34:1461-70.
9. Harikrishnan S, Sunder KR, Tharakan JM, Titus T, Bhat A, Sivasankaran S, et al. Saccular coronary aneurysms: Angiographic and clinical profile and follow-up of22 patients. Indian Heart J 2000;52:178-
82.
10. Swanton RH, Thomas ML, Coltart DJ, Jenkins BS, Webb-Peploe MM, Williams BT. Coronary artery ectasia-- a variant ofocclusive arteriosclerosis. Br HeartJ 1978;40:393-400.
11. Baman TS, Cole JH, Devireddy CM, Sperling LS. Risc factors and outcomes in patients with coronary artery aneurysms. Am J Cardiol 2004;93:1549-51.
12. Altinbas A, Nazli C, Kinay O, Ergene O, Gedikli O, Ozaydin M, et al. Predictors of exercise induced myocardial ischemia in patients with isolated coronary artery ectasia. Int J Cardiovasc Imaging 2004;20:3-17.
13. Robinson FC. Aneurysm ofthe coronary arteries. Am HeartJ 1985;109:129-35.
14. Sorrell VL, Davis MJ, Bove AA. Current knowledge and significance ofcoronary artery ectasia: a chronologic review ofthe literature, recommendations for treatment, possible etiologies, and future considerations. ClinCardiol 1998;21:157-60.
15. Dralle JG, Turner C, Hsu J, Replogle RL. Coronary artery aneurysm after angioplasty and atherectomy. AnnThorac Surg 1995;59:1030-5.
16. Tengiz I, Ercan E, Aliyev E, Sekuri C, Duman C, Altuglu I. Elevated levels ofmatrix metalloprotein-3 in patients with coronary aneurysm: A case control study. CurrControl Trials Cardiovasc Med 2004;13:10.
17. Kajinami K, Kasahima S, Oda Y, Koizumi J, Kadsuda S, Mabuchi H. Coronary ectasia in familial hypercholesterolemia: histopathologic study regarding matrixmetalloproteinases. ModPathol 1999;12:1174-
80.
18. Selke KG, Vemulapalli P, Brodarick SA, Coordes C, Gowda S, Salem B, et al. Giant coronary artery aneurysm: detection with echocardiography, computed tomography, and magnetic resonance imaging. Am
HeartJ1991;121:1544-7.
19. Berkalp B, Kervancioglu C, Oral D. Coronary artery aneurysm formation after balloon angioplasty and stent implantation. IntJCardiol 1999;69:65-70.
20. Tunick PA, Slater J, Kronzon I, Glassman E. Discrete atherosclerotic coronary artery aneurysm: a study of 20 patients. J Am Coll Cardiol
1990;15:279-82.
21. Sayın T, Doven O, Berkalp B, Akyurek O, Guleç S, Oral D. Exercise-induced myocardial ischemia in patients with coronary artery ectasia without obstructive coronary artery disease. Int J Cardiol 2001;78:143-9.
22. Gunduz H, Akdemir R, Binak E, Tamer A, Uyan C. Spontaneous rupture of a coronary artery aneurysm. Jpn Heart J 2004;45:331-6.
23.Stajduhar KC, Laird JR, Rogan KM, Wortham DC. Coronary arterial ectasia; Increased prevalence in patients with abdominal aortic aneurysm as compared to occlusive atherosclerotic peripheral vascular disease. Am Heart J 1993;125:86-92.

Thank you for copying data from http://www.arastirmax.com