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Asetil Salisilik Asit Tedavisine İyi Yanıt Veren Multipl Nekrobiyozis Lipoidika Diyabetikorum Olgusu

A Case Of Multiple Necrobiosis Lipoidica Diabeticorum: A Good Response To Acetylsalicylic Acid Treatment

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Abstract (2. Language): 
Necrobiosis lipoidica diabeticorum (NLD) is a rare, chronic and granulomatous skin disorder that affects 0.3% of diabetic patients. Although the etiology and pathogenesis of NLD is still controversial, it is thought that microangiopathy has an important role. Various medications have been previously used in the treatment of NLD. We have reported a case of NLD that successfully treated with salicylic acid.
Abstract (Original Language): 
Nekrobiyozis lipoidika diyabetikorum (NLD) diyabetik hastaların %0,3'ünü etkileyen, nadir görülen, kronik granülomatoz bir deri hastalığıdır. Etyopatogenezinin halen tam olarak bilinmemesine rağmen mikroanjiy-opatinin önemli rol oynadığı düşünülmektedir. NLD tedavisinde birçok farklı ilaç kullanılmıştır. Biz salisilik asitle başarılı bir şekilde tedavi edilen bir NLD olgusu sunuyoruz.
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REFERENCES

References: 

1. Nguyen K, Washenik K, Shupack J. Necrobiosis lipoidica diabeticorum treated with chloroquine. J Am Acad Dermatol 2002;46(2): 34-6.
2. Freinkel RK. Diabetes Mellitus. in Fitzpatrick TB, Eisen AZ, Wolf K, Freedberg IM, Austin KF (eds): Dermatology in General Medicine, New York: Mc Graw-Hill 2000; 1969-75.
3. Jabbour SA, Miller JL. Endocrinopathies and the
skin. Int J Dermatol 2000;39: 88-9.
4. Boyd SA. Tretinoin treatment of necrobiosis lipoidi-
ca diabeticorum. Diabetes Care 1999;22(10): 1753-4.
5. Boulton AJM, Cutfield RG, Abouganem D, Angus E, Flynn HW, Skyler JS, Penneys NS. Necrobiosis lipoidi-ca diabeticorum: A clinicopathologic study. J Am Acad Dermatol 1988;18(3): 530-7.
6. Noz KC, Korstanje MJ, Vermeer BJ. Ulcerating necrobiosis lipoidica effectively treated with pentoxi-fylline. Clin Exp Dermatol 1983;18: 78-9.
7. Gebauer K, Armstrong M. Koebner phenomenon with necrobiosis lipoidica diabeticorum. Int J Dermatol
1993;32: 895-6.
8. Erbağcı Z, Erbağcı İ, Özgöztaşı O. Tip II Diabetes mellitusta dermatolojik mikrovasküler komplikasyonlar ve diabetik retinopati. T Klin Dermatol 1999;9:68-74.
9. Sawada Y. Successful treatment of ulcerated necro-
Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi 2 0 0 1 ; 8 ( 3 ) : 1 2 - 15
Ozcanlı,
Multip
l nekrobiosis lipoidika diaybetikorum
15
biosis lipoidica diabeticorum with prostaglandin E1 and
skin flap transfer. J Dermatol 1985;12: 449-54.
10. Ling TC, Thomson KE, Goulden V, Goodfield MJD. PUVA teraphy in necrobiosis lipoidica diabetico-
rum. J Am Acad Dermatol 2002;46(2): 319-20.
11. Karkavitas K, Miller JA, Dowd PM, Kirby JD.
Aspirin in the management of necrobiosis lipoidica.
Acta Derm Venerol 1982;62: 183.
12. Colwell JA, Haluska PV, Sarji K. Altered platelet
function in diabetes mellitus. Diabetes 1976;25: 826¬31.
13. Brüngger A. Transkutane sauerstoff- und kohlen-dioxiddruckmessung bei necrobiosis lipoidica. Hautartz
1989;40: 231-2.
14. Beck HI, Bjerring P, Rasmussen I, Zachariae H, Stenbjerg S. Treatment of necrobiosis lipoidica diabeti-corum with low-dose acetylsalicylic acid: randomized
double blind trial. Acta Derm Venerol 1985;65: 230-4.
15. Mycek JM, Harvey RA, Champe CP, Fisher BD,
Cooper M. Anti-inflammatory drugs. Pharmacology,
Lippincott- Raven Publishers 1997;401-19.
16. Massoti G, Poggesi L, Galanti G, Abbate R, Neri Serneri GG. Differential inhibition of prostacyclin pro¬duction and platelet aggregation by aspirin. Lancet
1979;8(2):1213-7.

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