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VÜCUT KOMPOZİSYONU DEĞİŞİKLİKLERİNİ SAPTAMADA DUAL-ENERJİ X-RAY ABSORBSİYOMETRİ VE BİYOELEKTRİK İMPEDANS; BİR HEMODİYALİZ SEANSININ ETKİSİNİ SAPTAMA İKİ YÖNTEMİN KARŞILAŞTIRMALI ANALİZİ

THE COMPARISON OF DUAL-ENERGY X-RAY ABSORBTIOMETRY AND BIOELECTRIC IMPEDANCE ANALYSIS IN DETERMINATION OF BODY COMPOSITION IN HEMODIALYSIS PATIENTS

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Abstract (2. Language): 
Chronic renal failure causes changes in body composition. Dual-Energy X-Ray Absorbsiometry (DEXA) and bioelectric impedance analysis (BIA) are the techniques to evaluate body composition in chronic renal failure. In the present study, we aimed to perform comparative analysis of DEXA and BIA in determination of minor changes in body composition occurring during single dialysis session. Each patient was weighed and body composition was measured by DEXA and BIA before and after dialysis. When measurements before and after dialysis by DEXA were considered, changes in fat mass and bone mineral content were not statistically significant, whereas lean body mass and total weight measurements before and after dialysis differed significantly. BIA was considered, fat mass, lean body mass and water content before and after dialysis were found to be statistically significantly different. When results obtained by DEXA BIA were compared differences in means of EM and LBM were not statistically significant and they were found to be positively correlated. As a conclusion; DEXA is a quite sensitive technique in determination of FM, LBM and bone mineral content and can be used in dialysis patients to determine short and long term changes in body composition. Despite BIA is less reliable in determination of body composition, it can be still used in determination of dry weight in conjunction with clinical parameters since it is a noninvasive and easy to perform technique at bedside.
Abstract (Original Language): 
Kronik böbrek yetmezliği (KBY), vücut kompozisyonunda değişiklikler oluşturan önemli bir süreçtir. Dual-Enerji X-Ray Absorbsiyometri (DEXA) ve Biyoelektrik impedans analiz (BİA), KBY hastalarında vücut kompozisyonunu değerlendirmede kullanılan yöntemlerdir. Çalışmamızda bir diyaliz seansı sırasında oluşan küçük vücut kompozisyonu değişikliklerini saptamada DEXA ve BİA ölçümlerinin karşılaştırmalı analizini yapmayı amaçladık. Hastalar diyaliz öncesi ve sonrası elektronik tartı ile tartıldı, DEXA ve BİA ile vücut kompozisyonu ölçümleri yapıldı. DEXA ile diyaliz öncesi ve sonrası değerler karşılaştırıldığında kemik mineral içerik ve yağ dokusunda değişiklik saptanmazken, yağsız vücut kulesindeki azalma miktarı 2.53 kg idi ve elektronik tartı ile saptanan değer ile arasında korelasyon mevcuttu (r= 0.6923). BİA ile elde edilen sonuçlarda diyaliz öncesi ve sonrası yağ miktarı, yağsız doku miktarı, su miktarı değerlerinde istatistiksel olarak anlamlı değişiklikler saptandı (p<0.05). DEXA 'nın yağ miktarı, yağsız vücut kitlesi ve kemik doku miktarını belirlemede oldukça duyarlı bir yöntem olduğu kanısına vardık. BİA ise, daha az güvenilir bir yöntem olmakla birlikte uygulamadaki kolaylıkları nedeniyle klinik parametrelerle birlikte kullanılabilir sonucuna vardık.
FULL TEXT (PDF): 
244-248

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