Buradasınız

Anasayfa » Content

RENAL TRANSPLANTASYON SONRASI HUMAN PAPİLLOM VİRÜS OLGUSU

THE CASE OF HUMAN PAPILLOMAVIRUS IN POST RENAL TRANSPLANTATION

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The prevalance of human papillomavirus induced infection is high in women who had trans pi at at ion. In this case report, a 22-years-old girl, sexually inactive, had papilloma caused by human papillomavirus on her 1 lth years after transplantation. By the time she was admitted to the hospital for urinary infection, she was complaining of itching at vulva. After having the result of Candida albicans growing in the culture, antifungal treatment was started to the patient. During the following days she continued to complain of white coloured dischange and pruritus. After gynecological examination she was diagnosed as condylomata acuminata. She was prescibed fluconazole and undergone surgical excision and electrocauterization .Microscopic examination of sample was consistent with inverted papilloma. Low risked human papillomavirus was found in hybridization method. After three weeks, cryotherapy was applied. Any recurrent lesions were not seen in 9 months follow-up. The controls were planned every 6 months. In conslusion, human papillomavirus infection is more common in transplant patients. Development of malignancy can be prevented by frequent screening of human papillomavirus infection.
Bookmark/Search this post with
Abstract (Original Language): 
Renal transplant kadınlarda servikal human papillom virus infeksiyonu prevalansı yüksektir. Bu olgu sunumunda, seksüel açıdan inaktif bir hastada posttransplant 11. yılda human papillom virusa bağlı papillom gelişimi bildirilmektedir. Yirmi iki yaşında kız hasta. Posttransplant 11. yılda üriner sistem infeksiyonu nedeniyle hospitalize edilen hastanın vulva kaşıntısı tanımlanıyordu. Mikotik kültüründe Candida tropikalis üreyen hastaya antimikotik tedavi başlandı. İzleminde beyaz renkli vaginal akıntı ve kaşıntısı devam etti. Jinekolojik olarak condiloma accumunata tanısı kondu. Flukanazol, loop eksizyon ve elektrokoterizasyon uygulandı. Lezyonun mikroskopik incelemesi inverted papillom ile uyumlu bulundu. Hibridizasyon yönteminde düşük riskli human papillom virus (+) bulundu. Üç hafta sonra kriyoterapi uygulandı. Dokuz aylık izleminde lezyon saptanmadı. Altı aylık kontrollerle izlemiplanlandı. Sonuç olarak; Transplante hastalarda human papillom virus infeksiyonları daha sıktır. Belirli aralarla yapılan human papillom virus taraması ile malignite gelişimi önlenebilir.
FULL TEXT (PDF): 
PDF icon pdf_tndt_460.pdf
  • 4
236-238
  • Turkish

REFERENCES

References: 

1. Özsaran AA, Ateş T, Dikmen Y, et al. Evaluation of the cervical intraepithelial neoplasia and human papiloma virus infection in renal transplant patients receiving immunosuppressive therapy. Eur J Gynecol Oncol 1999; 2: 127-130.
2. Sillman FH, Sentovich S, Shaffer D. Anogenital neoplasia in renal transplant patients. Ann
Transplant 1997; 4: 54-66.
3. Mayerson D, Badia JI, Wild R et al. Genital
intraepithelial lesions in immunsuppressed female patients after renal transplant: cytologic, and histologic study. Rev Med Chil 1991; 11: 1254¬1258.
4. Tjiong MY, Out TA, Ter Schegget J et al.
Epidemiologic and mucosal immunologic aspects of HPV infection and HPV-related cervical neoplasia in the lower female genitale tract: A review. Int J Gynecol Cancer 2001; 11: 9-17.
5. Lorincz AT, Reid R, Jenson AB et al. Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types.
Obstet Gynecol 1992; 79: 328-337.
6. Hinchliffe SA, Van Velzen D, Korporal H et al. Transience of cervical HPV infection in sexually active, young women with normal cervicovaginal
cytology. Br J Cancer 1995; 72: 943-945.
7. Burk RD, Ho GY, Beardsley L et al. Sexual
behavior and partner characteristics are the predominant risk factors for genital human papillomavirus infection in young women. J Infect
Dis 1996; 174:679-689.
8. Melkert PW, Hopman E, van den Brule AJ, et al. Prevalence of HPV in cytomorphologically normal cervical smears, as determined by the polymerase chain reaction, is age-dependent. Int J Cancer
1993;53:919-923.
9. Arends MJ, Buckley CH, Wells M. Etiology,
pathogenesis, and pathology of cervical neoplasia. J Clin Pathol 1998;51:96-103.
10. Kirnbauer R, Taub J, Greenstone H et al. Efficient self-assembly of human papillomavirus type 16, LI and L1-L2 into virus-particles. J Virol 1993;
67: 6929-6936.
11. Hagensee ME, Koutsky LA, Lee SK et al. Detection of cervical antibodies to human papillomavirus type 16 (HPV-16) antigens in relation to detection of HPV-16 DNA and cervical
lesions. J Infect Dis 2000; 181: 1234-1239.

Thank you for copying data from http://www.arastirmax.com