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Nefrotik Sendromlu 84 Olgunun Retrospektif Analizi

The Retrospective Analysis of 84 Patients With Nephrotic Sydrome

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The frequency of histologic types of glomerulonephritis vary depending on ethnicity and geographic location. Characteristics of 84 patients with nephrotic syndrome admitted to Dicle University Faculty of Medicine were retrospectively analysed. The mean age of 41 female and 43 male patients was 35.0 years. Forty-seven pa¬ tients (78.3%) had primary glomerulonephritis and the remaining 13 patients (21.7%) had secondary glomerulonephritis. The basal mean values of patients with NS were as follows: serum creatinine 1.68 mg/dl, serum urea 64.5 mg/dl, renal protein loss 5.7 gr/day, and creatinine clearence 65 ml/min. MPGN and MGN were the most common GN types in biopsies performed with a NS indicati¬ on. In our study, MPGN, a decreasing type in developed countries, and M G N , the most common type worldwide were at top. Altho¬ ugh MPGN is decreasing in western countries it is still common in different regions of our country and is the most common GN type in our region.
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Abstract (Original Language): 
Glomerülonefritlerin (GN) histolojik tipleri, coğrafi yerleşim, etnisiteye bağlı olarak farklı olmaktadır. 2001-2005 arasında Dicle Üniversitesi Tıp Fakültesi Nefroloji Bilim Dalı'na başvuran ve nefrotik sendrom tanısı alan 84 hastanın özellikleri retrospektif olarak değerlendirildi. Kırk bir kadın ile 43 erkek hastanın yaş ortalaması 35.0 hesaplandı. Hastalardan 60'ına (%71.4) renal biyopsi ile histopatolojik tanı konmuştu. Bunların 47'si (%78.3) primer GN, geri kalan 13 hasta (%21.7) sekonder GN tanısı aldı. NS'li olguların bazal değerleri, kreatinin 1.68 mg/dl (0.3-11.5), üre 64.5 mg/dl (10-350), idrarla protein atılımı 5.7 gr/gün (1.5-14.8), kreatinin klirensi 65 ml/dk (5¬ 156) olarak hesaplandı. Ülkemizde NS endikasyonu ile renal biyop¬ si yapılan hastalarda MPGN ve M G N en sık GN tipleri olarak karşımıza çıkmaktadır. Çalışmamızda da primer GN'ler arasında gelişmiş ülkelerde azalma gösteren MPGN ve dünyada sık görülen MGN ilk iki sırada bulundu. Batı ülkelerinde azalan ama ülkemizin değişik bölgelerinde sıklığını koruyan MPGN bölgemizde de halen ilk sıra¬ daki yerini korumaktadır.
FULL TEXT (PDF): 
PDF icon pdf_tndt_532.pdf
  • 3
119-122
  • Turkish

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