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Mesane Rabdomiyosarkomund a Böbrek Fonksiyonlarında Bozulma Nedenleri

Multiple Causes of Renal Functional Deterioration in Bladder Rhabdomyosarcoma: Case Report

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2006

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The tumors that affect bladder, prostate and testis in children are rare. Here we report a case of bladder rhabdomyosarcoma presenting with hypertension and acute renal failure. Acute renal failure and hypertension have been treated successfully by appropiate medical and surgical interventions but the current problem is chronic renal failure and recurrent urinary tract infections. Beyond multiple difficult problems of a cancer patient confronting the pediatric oncologist we want to emphasize an additional nephro-urological morbidity. The causes of renal functional impairment in patients with bladder rhabdomyosarcoma are discussed. The importance of nephro-urological problems and the clinical value of nephrological follow-up in cancer patients is emphasized.
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Abstract (Original Language): 
Çocuklarda mesane, prostat ve testis tümörleri çok ender görülmektedir. Bu yazıda hipertansiyon ve akut böbrek yetersizliği ile başvuran mesane rabdomiyosarkom olgusu sunulmuştur. Akut böbrek yetersizliği ve hipertansiyon uygun medikal ve cerrahi yak¬laşım ile tedavi edilmesine karşın hastada yineleyen idrar yolu enfeksiyonları ve kronik böbrek yetersizliği gelişmiştir. Pediyatrik on-kologlar kanser hastalarının tedavisinde nefro-ürolojik morbidite de dahil pek çok problemle karşılaşmaktadırlar. Yazımızda mesane rabdomiyosarkom olgularında renal fonksiyonlarda bozulmaya yol açan nedenler tartışılmakta ve nefrolojik izlemin önemi vurgulan¬maktadır.
FULL TEXT (PDF): 
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  • 2
122-128
  • Turkish

REFERENCES

References: 

1. Chertin B, Reinus C, Koulikov D, Rosenmann E, Farkas A, Chertin B. Post-chemotherapy microscopic residual prostate rhabdomyosarcoma: long-term conservative follow-up. Pedi-atr Surg Int 2002;18:68-9.
2. Kaefer M, Rink RC. Genitourinary rhabdomyosarcoma. Urol Clin North Am 2000;27(3):471-87.
3. Sklar CA, LaQuaglia MP. The long-term complications of che¬motherapy in childhood genitourinary tumors. Urol Clin North Am 2000;27(3):563-8.
4. Merguerian PA, Agarwal S, Greenberg M, Bagli DJ, Khoury AE, Mc Lorie GA. Outcome anlysis of rhabdomyosarcoma of the lower urinary tract. J Urol 1998;160:1191-4.
5. Lambert H, Coulthard M. The child with urinary tract infecti¬on. In: Webb N, Postlethwaite R (eds), Clinical Paediatric Nephrology. Oxford, 3rd edition, 2003, pp 197-226.
6. Coroneos E, Assouad M, Krishnan B, Truong LD. Urinary obstruction causes irreversible renal failure by inducing chro¬nic tubulointerstitial nephritis. Clin Nephrol 1997;48(2):125-8.
7. Kher KK. Obstructive uropathy. In: Kher KK, Makker SP (eds), Clinical Pediatric Nephrology. McGraw Hill, 1992, pp 447-65.
8. Heij HA, Vos A, De Kraker J, Voute PA. Urogenital rhabdom-yosarcoma in children: is a conservative surgical approach justified? J Urol 1993;150:165-8.
9. Schwarz A, Perez-Canto A. Nephrotoxicity of antiinfective
drugs. Int J Clin Pharmacol Ther 1998;36(3):164-7.
10. Izzedine H, Launay-Vacher V, Isnard-Bagnis C, Deray G. Drug-induced Fanconi's syndrome. Am J Kidney Dis 2003;
41(2):292-309.
11. Woodland C, Ito S, Granvil CP, Wainer IW, Klein J, Koren G.
Evidence of renal metabolism of ifosfamide to nephrotoxic
metabolites. Life Sci 2000;24:68(1):109-17.
12. Loebstein R, Atanackovic G, Bishai R, et al. Risk factors for
Official Journal of the Turkish Society of Nephrology / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
127
Multiple Causes of Renal Functional Deterioration in Bladder Rhabdomyosarcoma: Case Report
long-term outcome of ifosfamide-induced nephrotoxicity in
children. J Clin Pharmacol 1999;39(5):454-61.
13. Garin E, Devillers A, Rivalan J, et al. Contribution of 99Tcm-DMSA scintigraphy to aetiological diagnosis in renal transp¬lant recipients with impaired renal function. Nucl Med Com-
mun 2000;21(1):77-81.
14. Yamada M. Assessment of 99mTc-DMSA renography and up¬take compared with creatinine clearance in rats with drug-in¬duced nephrotoxicity-II. Cisplatin-induced nephrotoxicity. Kaku Igaku 1991;28(4):347-54 (abstract).
15. Yamada M. Assessment of 99mTc-DMSA renography and up¬take compared with creatinine clearance in rats with drug-in-
duced nephrotoxicity-I. Gentamicin-induced nephrotoxicity.
Kaku Igaku 1991;28(4):339-45 (abstract).
16. Caglar M, Yaris N, Akyuz C. The utility of (99m)Tc-EC scin-
tigraphy for early diagnosis of ifosfamide induced nephroto-xicity. Nucl Med Commun 2001;22(12):1325-32.
17. Morrison SC, O'Donnell JK. Ifosfamide-induced alteration of technetium-99m-DMSA renal parenchymal imaging. J Nucl
Med 1997;38:1811-2.
18. Anninga JK, Olmos RAV, de Kraker J Van Tinteren H, Hoef-nagel CA, Van Royen EA. Technetium-99m-dimercaptosucci-nic acid and ifosfamide tubular dysfunction in children with
cancer. Eur J Nucl Med 1994;21:658-62.

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