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Diyabetik Olmayan Sürekli Ayaktan Periton Diyalizi Hastalarında Serum Kolesterol Seviyeleri ile Beslenme Parametreleri ve Antropometrik Ölçümler Arasındaki İlişkinin Değerlendirilmesi

The Evaluation of the Association Between Serum Cholesterol Levels with Nutritional Parameters and Anthropometric Measures in Non-Diabetic Continuous Ambulatory Peritoneal Dialysis Patients

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Abstract (2. Language): 
We evaluated the association of serum cholesterol levels with nutritional parameters and anthropometric measurements in non-diabetic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) treatment. Thirty-nine (21 males, 18 females) patients were enrolled into the study. The patients were divided into two groups as group 1 (n=20, serum cholesterol ≥ 200 mg/dl), and group 2 (n=19, serum cholesterol < 200 mg/dl.) according to serum cholesterol levels. A positive correlation was found between serum levels of cholesterol and prealbumin (r=0.428, p=0.007), transferrin (r=0.322, p=0.046), triglyceride (r=0.537, p=0.001), LDLC (r=0.739, p<0.001), and HDL-C (r=0.454, p=0.004), and between BMI and FM (r=0.851, p<0.001), FFM (r=0.503, p=0.001), TBW (r=0.522, p=0.001) and MAMC (r=0.849, p<0.001). BIA in group 1 was higher than group 2 (p = 0.007). No statistical relation was found between serum cholesterol, and the anthropometric measurements. In conclusion, we found a positive correlation between serum cholesterol levels and prealbumin and transferrin but not in anthropometric measurements in CAPD patients. Further, large scale studies are needed to conclude an absolute judgement.
Abstract (Original Language): 
Bu çalışmada diyabetik olmayan Sürekli Ayaktan Periton Diyaliz (SAPD) tedavisi alan hastalarda serum kolesterol seviyeleri ile beslenme parametreleri ve antropometrik ölçümler arasındaki ilişkiyi değerlendirdik. 39 hasta (21 kadın, 18 erkek) çalışmaya alındı. Hastalar serum kolesterol seviyelerine göre grup 1 (n = 20, serum kolesterol ≥ 200 mg/dl) ve grup 2 (n = 19, serum kolesterol < 200 mg/dl) olarak ikiye ayrıldı. Serum kolesterol ile prealbumin (r=0,428, p=0,007), transferin (r=0,322, p=0,046), trigliserid (r=0,537, p=0,001), LDL-K (r=0,739, p<0,001) ve HDL-K (r=0,454, p=0,004) arasında pozitif korelasyon ve vücut kitle indeksi (VKİ) ile yağ kitlesi(YK) (r=0,851, p<0,001), serbest yağ kitlesi (SYK) (r=0,503, p=0,001), total vücut suyu (TVS) (r=0,522, p=0,001) ve orta kol kas çevresi (OKKÇ) (r=0,849, p<0,001) arasında da pozitif korelasyon saptandı. Bioelektrik impedans analiz (BIA) grup 1’de grup 2’ye göre daha yüksek idi (p=0.007). Serum kolesterol düzeyi ile antropometrik ölçümler arasında istatistiksel bir ilişki saptanmadı. Sonuç olarak, SAPD hastalarında serum kolesterol düzeyi ile prealbumin ve transferrin arasında pozitif korelasyon saptandı ancak antropometrik ölçümlerle korelasyon saptanmadı. Bu konuda daha kesin yargıya varmak için daha geniş kapsamlı ileri araştırmalara gereksinim vardır.

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