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Periton Diyalizi Hastalarında Sen Virüsü Varyantı Olan Senv-D ve Senv-H’nin Prevalansı

Prevalence of Senv-D and Senv-H Variants of Sen Virus in Peritoneal Dialysis Patients

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2009

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
OBJECTIVE: Patients on peritoneal dialysis are at high risk of blood-borne infections due to frequent blood transfusions. We aimed to determine and compare the prevalence of SENVD and SENV-H variants of the SEN virus (SENV) in these patients. MATERIAL and METHOD: A total of 143 subjects, 43 on peritoneal dialysis and 100 healthy controls, were included in this point-prevalence study. SENV-D and SENV-H DNAs were detected with the polymerase chain reaction. RESULTS: The prevalence of SENV-D was 23.2% in peritoneal dialysis patients. The prevalence of SENV-H being 20.9% in peritoneal dialysis patients was found to be higher than that of SENV-D. SENV-H prevalence was not significantly higher in our patient population compared with healthy subjects (16.0%). On the other hand, SENV-D was significantly more prevalent in all patient groups compared to healthy control subjects (5.0%). There was no association between SENV and HCV. CONCLUSIONS: SEN virus infection, particularly SENV-D variant, has high prevalence in patients on peritoneal dialysis in Turkey. Care should be taken for SENV hepatitis and transmission of virus among these patients.
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Abstract (Original Language): 
AMAÇ: Kan transfüzyonları sebebiyle kan ile taşınan enfeksiyonlar periton diyalizi hastalarında daha sık görülür. Bu çalışmanın amacı, bu hastalarda SEN virüslerinin (SENV) SENV-D ve SENV-H tiplerinin sıklığını tespit etmek ve birbiriyle karşılaştırmaktır. GEREÇ ve YÖNTEM: 100 sağlıklı kontrol, 43 periton diyalizi hastası olmak üzere 143 hasta bu çalışmaya dahil edildi. SENV-D ve SENV-H DNA polymerase chain reaction yöntemi ile çalışıldı. BULGULAR: Periton diyalizi hastalarında; SENV-D sıklığı %23.2, SENV-H %20.9 bulundu. SENV-H sıklığı sağlıklı grup (%16.0) ile karşılaştırıldığında anlamlı olarak yüksek değildi. Diğer yandan SENV-D sağlıklı grup (%5.0) ile karşılaştırıldığında anlamlı olarak yüksek bulundu. SENV ile HCV arasında birliktelik tespit edilmedi. SONUÇ: SEN virüs enfeksiyonu ve özellikle SENV-D tipi Türkiye’deki periton diyalizi hastalarında sağlıklı gruba göre daha yüksek sıklıkla görülmektedir. SEN-V ve HCV arasında birliktelik tespit edilmemiştir.
FULL TEXT (PDF): 
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  • 3
107-111
  • Turkish

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Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
Turkish Nephrology, Dialysis and Transplantation Journal
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