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Renal Transplant Alıcılarında Enkapsüle Peritoneal Skleroz Gelişimi: Risk Faktörleri ve Klinik Sonuçları

Development of Encapsulating Peritoneal Sclerosis in Kidney Allograft Recipients: Risk Factors and Clinical Implications

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2011
DOI: 
10.5262/tndt.2011.1002.04

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
OBJECTIV ES: Although bowel obstruction due to encapsulating peritoneal sclerosis (EPS) is a rare complication following kidney transplantation, all our patients were previous peritoneal dialysis (PD) patients. The aim of this study was to investigate the incidence and risk factors for development of bowel obstruction due to EPS in kidney allograft recipients previously treated with PD. METARIAL and Metho ds: We retrospectively recruited 31 PD patients who had kidney transplantation between 1999 and 2009. Development of postoperative bowel obstruction due to EPS was further analysed for the risk factors. Res ults : Four patients (12.9%) developed bowel obstruction due to EPS in post-transplant period (minimum 7 days to maximum 24 months). Three patients underwent surgical adhesiolysis and intestinal resection due to ischemia and one patient in this group lost the graft due to renal graft artery thrombosis during the bowel obstruction period. The fourth was resolved with conservative treatment. PD duration and the number of peritonitis attacks were the statistically significant risk factors for development of bowel obstruction due to EPS (p=0.0018 and p=0.004, respectively). ConclusIo n: Bowel obstruction due to EPS can be seen after kidney transplantation in PD patients and it needs surgical treatment in most cases. PD duration and number of previous peritonitis attacks are the risk factors for post-transplant EPS development
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Abstract (Original Language): 
AMA Ç: Renal transplantasyon sonrasında enkapsüle peritoneal skleroz (EPS) gelişimi nadir görülmesine rağmen, tüm olgularımız daha once periton diyalizi (PD) uygulanan hastalardan oluşmaktadır. Bu çalışmanın amacı, daha once PD ile tedavi edilen renal transplant alıcılarında EPS nedeni ile gelişen ileus sıklığını, risk faktörlerini ve klinik sonuçlarını ortaya koymaktır. GEREÇ ve YÖN TEML ER: 1999-2009 yılları arasında PD tedavisi uygulanmakta olan 31 hastaya renal transplant yapılmış olup bu olgular çalışmaya alındı. Transplantasyon sonrası EPS nedeni ile ileus gelişen hastalar risk faktörleri yönünden ayrıntılı incelendi. BUL GULA R: Toplam 4 hastada (%12,9) EPS gelişimine bağlı ileus yaşandı (en az 7 gün-en uzun 24 ay). Bunlardan 3 hasta cerrahi olarak tedavi edilirken (adhesiolysis ve iskemi nedeni ile intestinal rezeksiyon) cerrahi tedavi uygulanan hastalardan birisi ileus sırasında renal arter trombozu gelişerek greftini kaybetti. Son hasta ise cerrahi uygulanmadan koruyucu tedavi ile düzeldi. PD süresi ve peritonit atak sayısı EPS ve ileus gelişimi için anlamlı risk faktörleri olarak saptandı (p=0,0018 ve p=0,004, sırası ile). SONU Ç: EPS ve ileus renal transplant sonrasında özellikle daha once PD ile tedavi edilen olgularda gözlenebilmektedir ve çoğu olguda cerrahi tedavi gerektirmektedir. PD süresi ve peritonit atak sayısı anlamlı risk faktörleri olarak dikkati çekmektedir.
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  • 2
142-145
  • Turkish

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