Buradasınız

Nefrotik Sendromun Nadir Bir Nedeni: C1q Nefropatisi

A Rare Cause of the Nephrotic Syndrome: C1q Nephropathy

Journal Name:

Publication Year:

DOI: 
DOI 10.5262/tndt.2012.1002.18

Keywords (Original Language):

Abstract (2. Language): 
C1q nephropathy is a rare cause of idiopathic nephrotic syndrome seen in children and young adults. Mesangial proliferation with deposition of C1q in the mesangium on immunofluorescence examination is the main pathological feature of the disease. Diagnosis is made by ruling out systemic lupus erythematosus with clinical and laboratory investigation. In this report, we discussed a patient presenting with nephrotic syndrome and C1q nephropathy with a review of the relevant literature.
Abstract (Original Language): 
C1q nefropatisi; sıklıkla çocuklarda ve genç erişkin yaş grubunda görülen, nadir, idiyopatik nefrotik sendrom nedenlerindendir. Temel patolojik özelliği, mezengial proliferasyon ile birlikte immünfloresan değerlendirmede mezengial C1q depolanması olup; tanı için klinik ve laboratuvar bulguların varlığı yanında, sistemik lupus eritematozusun ekarte edilmesi gerekmektedir. Bu yazıda, C1q nefropatisi tanısı konulan bir olgu, literatürden gözden geçirilerek sunulmuştur.
195-197

REFERENCES

References: 

1. Jennette JC, Hipp CG: C1q nephropathy: A distinct pathologic
entity usually causing nephrotic syndrome. Am J Kidney Dis 1985;
6 (2): 103-110
2. Vizjak A, Ferluga D, Rozic M, Hvala A, Lindic J, Levart TK, Jurcić
V, Jennette JC: Pathology, clinical presentations and outcomes of
C1q nephropathy. J Am Soc Nephrol 2008; 19 (11): 2237-2244
3. Roberti I, Baqi N, Vyas S, Kim DU: A single-center study of C1q
nephropathy in children. Pediatr Nephrol 2009; 24 (1): 77-82
.4. Markowitz GS, Schwimmer JA, Stokes MB, Nasr S, Seigle RL,
Valeri AM, D’Agati VD: C1q nephropathy: A variant of focal
segmental glomerulosclerosis. Kidney Int 2003; 64 (4): 1232-1240
5. Iskandar SS, Browning MC, Lorentz WB: C1q nephropathy: A
pediatric clinicopathologic study. Am J Kidney Dis 1991; 18 (4):
459-465
6. Fukuma Y, Hisano S, Segawa Y, Niimi K, Tsuru N, Kaku Y, Hatae K,
Kiyoshi Y, Mitsudome A, Iwasaki H: Clinicopathologic correlation
of C1q nephropathy in children. Am J Kidney Dis 2006; 47 (3):
412-418
7. Mii A, Shimizu A, Masuda Y, Fujita E, Aki K, Ishizaki M, Sato
S, Griesemer A, Fukuda Y: Current status and issues of C1q
nephropathy. Clin Exp Nephrol 2009; 13 (4): 263-274
8. Hisano S, Fukuma Y, Segawa Y, Niimi K, Kaku Y, Hatae K, Saitoh
T, Takeshita M, Iwasaki H: Clinicopathologic correlation and
outcome of C1q nephropathy. Clin J Am Soc Nephrol 2008; 3 (6):
1637-1643
9. Sharman A, Furness P, Feehally J: Distinguishing C1q nephropathy
from lupus nephritis. Nephrol Dial Transplant 2004; 19: 1420-1426
10. Davenport A, Maciver AG, Mackenzie JC: C1q nephropathy: Do
C1q deposits have any prognostic significance in the nephrotic
syndrome? Nephrol Dial Transplant 1992; 7: 391-396

Thank you for copying data from http://www.arastirmax.com