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Kolonoskopi Sonrası Görülen Akut Fosfat Nefropatisi Olgusu

A Case of Acute Phosphate Nephropathy After Colonoscopy

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2013
DOI: 
DOI 10.5262/tndt.2013.1001.19

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Acute phosphate nephropathy is a form of acute kidney injury (AKI) due to oral sodium phosphate (ONaP) purgatives used for bowel cleansing before colonoscopy. Usually, 45 ml ONaP is given two times daily 12-24 hours prior to colonoscopy. Intestinal absorption is followed by transient hypocalcemia and hyperphosphatemia in almost all patients. In addition, severe hyperphosphatemia, symptomatic hypocalcemia, hypernatremia, hypocalcemia, hyponatremia, hypokalemia, high anion gap metabolic acidosis and AKI can be seen. The patient presented in this paper is a 65-year-old female. She was diagnosed with type 2 diabetes mellitus and hypertension. Colonoscopy was performed in order to investigate the etiology of iron deficiency anemia. ONaP was administered for preparation of colonoscopy and AKI which was clinically compatible with APN developed after the procedure.
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Abstract (Original Language): 
Akut fosfat nefropatisi (APN) kolonoskopi öncesi bağırsak temizliği için kullanılmakta olan oral sodyum fosfat (ONaP) içeren purgatiflere bağlı görülen bir akut böbrek hasarı formudur. Genellikle kolonoskopi yapılacak olan hastalara işlemden 12-24 saat önceden başlayarak iki kez 45 ml’lik ONaP verilmektedir. İntestinal emilim olmakta ve geçici hiperfosfatemi ile hipokalsemi hemen her hastada görülmektedir. Bunun yanı sıra ciddi hiperfosfatemi, semptomatik hipokalsemi, hipernatremi, semptomatik hiponatremi; hipokalemi, yüksek anyon açıklı metabolik asidoz ve akut böbrek hasarı (ABH) görülebilmektedir. Bu yazıda sunulan olgu 65 yaşında kadın olup tip 2 diyabet ve hipertansiyon tanıları mevcuttu. Demir eksikliği anemisinin etiyolojisinin araştırılması amacıyla kolonoskopi yapılmıştı. ONaP ile kolonoskopi hazırlığı yapılmış ve işlem sonrası klinik olarak APN ile uyumlu ABH gelişmişti.
FULL TEXT (PDF): 
PDF icon arastrmx_172977_22_pp_117-119.pdf
  • 1
117-119
  • Turkish

REFERENCES

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