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Wegener Granülomatozu: Olağandışı Klinik Seyirli İki Olgu

Unusual Case Presentations of Wegener’s Granulomatosis

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DOI: 
10.5262/tndt.2013.1002.12
Abstract (2. Language): 
Wegener’s granulomatosis (WG) is an uncommon condition characterized by necrotizing granulomatosis of the upper and lower respiratory tract and glomerulonephritis. Clinical symptoms and organ involvement of the disease vary widely. In this report we describe two cases of WG with unusual clinical presentations: one presented with erosive monoarthritis of the right knee and the other with serous otitis media. These symptoms were preceded by renal and pulmonary involvement. We think that this report will increase the awareness about the unusual clinical presentations of WG. This report also highlights the importance of early aggressive management to avoid further severe complications in WG.
Abstract (Original Language): 
Wegener granülomatozu (WG), üst ve alt solunum yolunda nekrotizan granülomlar ve glomerülonefrit ile karakterize, nadir bir hastalıktır. Hastalığın klinik belirtileri ve organ tutulumu büyük ölçüde değişmektedir. Bu olgu sunumunda, akciğer ve böbrek tutulumu belirtileri ve bulguları meydana çıkmadan once, nadir klinik bulguları olan, biri sağ dizde eroziv monoarthrit ve diğeri seröz otitis media ve nazofarengeal kitle bulunan iki vaka takdim etmek istedik. Bu raporun WG’nun alışılmadık klinik başlangıcı hakkında farkındalığı arttırıcı etkisi olacağını düşünüyoruz. Ayrıca WG’da daha ciddi komplikasyonları önlemek için erken agresif tedavinin önemini vurgulamayı amaçlıyoruz.
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