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Canlı Böbrek Nakli Verici Adaylarının Elenme Nedenleri: Tek Merkez Deneyimi

Exclusion Reasons of Living Kidney Donor Candidates: A Single-Center Experience

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2014
DOI: 
10.5262/tndt.2014.1002.06

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
OBJECTIVE: Due to severe organ shortage, living kidney donors are important choices for transplantation. In Muslim countries, such as Turkey, living kidney donors are the main source of donor pool. In the literature, reasons for living donor exclusion are reported from several countries. However, there is no published study that focused on exclusion reasons of donor candidates in Turkey where living kidney transplantation rate is 73.4%. The goal of this retrospective study was to examine the exclusion reasons for donation among living kidney donor candidates at a single center in Turkey. MATERIAL and METHODS : A total 538 adults were evaluated as a living kidney donor candidate between December 1988 and January 2012. Evaluation outcome, exclusion reasons and demographic data were examined from electronic file system and immunology laboratory records. RESUL TS: In this period 451 kidney transplantations (38.6% cadaveric, 61.4% living donor) was performed. Overall 261 (48.5%) donor candidates who underwent evaluation could not donate. We were able to find the precise cause of exclusion of 86 donors (33%). Among excluded donor candidates the most common exclusion reason was medical causes (64%) such as diabetes mellitus, low glomerular filtration rate and hypertension. CONCLUS ION: Our study suggests that medical causes are significant exclusion reasons for living kidney donation at our center.
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Abstract (Original Language): 
AMAÇ: Organ bağışının istenilen düzeyde olmaması nedeni ile canlı böbrek nakli verici adayları, böbrek nakli için önemli kaynak oluşturmaktadır. Türkiye gibi Müslüman ülkelerde bu durum daha da belirgindir. Literatürde çeşitli ülkelerden böbrek nakli için canlı verici adaylarının elenme nedenlerini bildiren çalışmalar mevcuttur. Canlı böbrek nakli oranının %73,4 olduğu ülkemizden ise verici adaylarının elenme nedenlerine yönelik bir çalışma bulunmamaktadır. Çalışmamızın amacı, retrospektif olarak canlı böbrek nakli verici adaylarının elenme nedenlerini değerlendirmektir. GEREÇ ve YÖNTEMLER: Çalışmaya Aralık 1988 ve Ocak 2012 tarihleri arasında merkezimize böbrek nakli verici adayı olarak başvurmuş 538 kişi dahil edilmiştir. Elektronik dosyaların ve immünoloji laboratuvar kayıtlarının taranması ile adaylık değerlendirme sonuçları, elenme nedenleri ve demografik bilgileri değerlendirilmiştir. BUL GUL AR: Çalışma süresince merkezimizde 451 böbrek nakli (%38,6 kadaverik, %61,4 canlı) gerçekleştirilmiştir. Adaylardan 261 (%48,5) kişi verici olamamıştır. Seksen altı (%33) adayın kesin elenme nedenine ulaşabilmiştir. Diyabetes mellitus, düşük glomerüler filtrasyon hızı ve hipertansiyon gibi medikal nedenler en önemli (%64) elenme nedeni olarak belirlenmiştir. SONU Ç: Merkezimize başvuran canlı böbrek nakli verici adaylarının, en sık elenme nedeni medikal nedenler olarak tespit edilmiştir.
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