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HEMODÎALÎZ HASTALARINDA TRANSPLANT ÖNCESİ VE SONRASI SOL VENTRİKÜL FONKSİYONLARININ DEĞERLENDİRİLMESİ

EVALUATION OF LEFT VENTRICULAR FUNCTION IN HEMODIALYSIS PATIENTS AFTER RENAL TRANSPLANTATION

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Abstract (2. Language): 
There are many factors (hypertension, anemia, hyperparathyroidism, AV fistula, hyperhydration electrolyte imbalance, uremic toxins) which affect the cardiac functions of hemodialysis patients. In this study 11 patients who received renal transplantation were evaluated echocardiographycally and results were compared with the echocardiographic findings of 11 healthy subjects. The age of patients ranged from 24 to 62 years (mean age was 39.6 ± 3.9 years), renal graft survival was 27.7 ± 4.0 months (1222 to 49 months). Before and after the transplantation the left ventricle end systolic diameter was measured ec-hocardiographycally as 32.1129.8 mm. respectively (p>0.05), end diastolic diameter was measured as 48.0147.4 mm. respectively (p>0.05), ejection fraction was 64.18 % I 65.27 % respectively (p>0.05). These values were significantly lower than the control valu¬es (p<0.05). As a result, myocardium of hemodialysis patients is subjected to important anatomical changes and renal transplantation does not totally correct this situation.
Abstract (Original Language): 
Hemodiyaliz hastalarında, kardiyakfonksiyonları etkileyen birçok faktör (hipertansiyon, anemi, A-V fis-tül, hiperparatiroidizm, hiperhidratasyon, elektrolit imbalansı, üremik toksinler) bulunmaktadır. Bu çalış¬mada böbrek transplantasyonu yapılan 11 hastanın transplant öncesi ve sonrası ekokardiyografik bulgu¬ları değerlendirilmiş, elde edilen bulgular 11 sağlıklı kişiden oluşan kontrol grubu ile karşılaştı/itmiştir. Hastaların yaşları 24-62 arasında değişmekte olup, yaş ortalaması 39.64 ± 3.92, böbrek greft yaşamı 27.73 ±4.01 aydır (12-49). Ekokardiyografik değer¬lendirmede transplant öncesi/sonrası sol ventrikül sis-tolsonu çapı 32.1129.8 mm (p>0.05), sol ventrikül di-astol sonu çapı, transplant öncesi/sonrası 48.0147.4 mm (p>0.05) bulunurken, ejeksiyonfraksiyonu, transplant öncesi/sonrası % 64.181 % 66.27(p>0.05) ola¬rak değerlendirilmiştir. Bu değerler kontrol grubun¬daki değerlerle karşdaşlırıldığında anlamlı derecede düşük bulunmuştur (p<0.05). Sonuç olarak hemodia-liz hastalarının miyokardiyumunda anatomik olarak ciddi, kalıcı değişiklikler gelişmekte ve böbrek trans¬plantasyonu ile bu değişiklikler ortadan kaldırılama-maktadır.
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115-118

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