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HEMODÎALÎZ VE ADPD TEDAVİSİ ALTINDAKİ HASTALARDA RENAL OSTEODİSTROFİ'NİN DEĞERLENDİRİLMESİ

EVALUATION OF RENAL OSTEODISTROPHY IN PATIENTS UNDERGOING HEMODIALYSIS VS CONTINUOUS AMBULATORY PERITONEAL DIALYSIS

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Abstract (2. Language): 
We performed this study in order to find the frequ¬ency and severity of renal osteodystrophy (ROD) in our patients with chronic renal failure who were eit¬her on hemodialysis or continuous ambulatory perito¬neal dialysis (CAPD) programs. We compared these two groups of patients in respect of ROD and divalent ion metabolism, to see whether there was any diffe¬rence which might be due to different dialysis met¬hods. 30 patients who were being followed by Ege University Dialysis unit were admitted to this study. 15 of the patients were receiving hemodialysis while the other half were on CAPD treatment. Divalent ion metabolism, and immunoreactive parathormone (iPT/1) levels were investigated in both groups. In ad¬dition, X-ray lesion, bone scans, and bone histology Were studied. In both hemodialysis and CAPD gro¬ups, mild ROD detected, but severity and bone frequ¬ency of ROD was not statistically different in either group.
Abstract (Original Language): 
Kronik böbrek yetmezliği olan, ayaktan devamlı periton diyalizi (ADPD) ve hemodiyaliz programındaki hastalarımıza renal Osteodistrofi (ROD) yaygınlığını ve derecesini değerlendirmek, her iki grup ara¬sında divalen iyon metabolizması ve ROD açısından bir farklılık olup olmadığını ortaya koymak amacıyla bu çalışmayı yaptık. Ege Üniversitesi diyaliz ünitesinde takip edilen, hemodiyaliz programından 15 has¬ta ve ADPD programından 15 hasta olmak üzere top¬lam 30 hasta çalışmaya alınmıştır. Değerlendirme biyokimyasal, radyolojik, sintigrafik ve histolojik ola¬rak yapıldı. Her iki çalışma grubumuzda divalen iyon metabolizması, vitamin D metabolizması, PTH ilişki-sindeki bozukluk, değerlendirmeye alınanparametre-lerde çeşitli derecelerde kendini göstermiştir. ADPD ve hemodiyaliz programında olan hastalarımızda ROD bulguları hafif düzeylerde bulundu. Gruplar arasında ROD yaygınlığı ve derecesi açısından fark¬lılık saptanmadı.
FULL TEXT (PDF): 
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